Analysis of factors affecting the length of hospitalization of patients with Clostridioides difficile infection: a cross-sectional study.

Background: Clostridioides difficile infection (CDI) is an infectious disease caused by the gram-positive, anaerobic bacterium C. difficile. The vulnerable populations for CDI include the elderly, immunocompromised individuals, and hospitalized patients, especially those undergoing antimicrobial therapy, which is a significant risk factor for this infection.

Exposure to nanoparticles of magnetite FeO in three different doses and their influence on selected respiratory parameters of bronchoalveolar lavage after intravenous instillation.

Objectives: Due to nano-dimensions (less than 100 nm), can nanoparticles probably penetrate through various membranes and travel from the bloodstream to other organs in the body. The aim of our study was to find out whether NPs FeO (coated with sodium oleate) injected into the tail vein of laboratory Wistar rats pass through the bloodstream to the respiratory tract (in comparison with a control group); and if so whether increasing doses of NPs FeO have an escalating harmful effect on selected bronchoalveolar lavage (BAL) parameters.

Methods: Wistar rats were intravenously given 3 doses of the suspension of NPs FeO (0.

Comparison of respiratory toxicity of TiO and FeO nanoparticles after intravenous instillation: an experimental study.

Objective: Nanomaterials consist of particles smaller than 100 nm - nanoparticles (NPs). Their nano dimensions allow them to penetrate through various membranes and enter into the bloodstream and disseminate into different body organs. Massive expansion of nanotechnologies together with production of new nanoparticles which have not yet been in contact with living organisms may pose a potential health problem.

Respiratory toxicity of TiO nanoparticles after intravenous instillation: an experimental study.

Objective: Nanomaterials are materials consisting of particles having one or more dimensions smaller than 100 nm. Nanoparticles (NP) have different properties and effects in comparison with the same particle materials of larger size. They can penetrate through various membranes and get from the bloodstream to other organs in the body.

Respiratory toxicity of Fe3O4 nanoparticles: experimental study.

Introduction: In the medical field, nanoparticles (NP) Fe3O4 are currently considered to be a relatively inert carrier for therapeutic and diagnostic pharmaceuticals, and they are also presumed for intravenous (i.v.) administration.

Combined effect of selected mineral fibres and tobacco smoke on respiratory tract in rats.

The rats were inhaling amosite and wollastonite fibres at two concentrations (30 and 60 mg/m3) one hour every second day and cigarette smoke of 3 cigarettes per day (with the exception of Saturdays and Sundays). They were sacrificed after 6 month of exposure. Bronchoalveolar lavage (BAL) was performed and selected inflammatory and cytotoxic parameters were examined.

Effect of TiO2 nanofibres on selected bronchoalveolar parameters in acute and subacute phase--experimental study.

Titanium dioxide nanofibres (TiO2) were intratracheally instilled in dose of 4 mg/0.2 mL saline solution per animal (Wistar rats). After 48 hours and 14 days the animals were exsanguinated (under i.

The influence of cigarette smoke on the selected bronchoalveolar cells in experiment.

Unlabelled: The occurence of lung diseases (obstructive, malignant) resulting from smoking has an increasing tendency. The lung is the primary organ at risk from the effects of inhaled cigarette smoke and smoking has been implicated as a contributing factor to the causation of various respiratory diseases. The aim of presented work was to find out the subchronic effect of the 6-month exposure to cigarette smoke on the selected inflammatory and cytotoxic parameters of bronchoalveolar lavage in W rats and thus to contribute to understanding of the mechanism of action of tobacco smoke and/or path mechanism of lung injury developed after cigarette smoking.

Long-term care in developed countries and recommendations for Slovak Republic.

The aging of our population represents a most significant demographic change. It represents important challenges and consequences for the nation's economic, social, and health institutions and for the health and well-being of older persons and their families. Old people over 60 are now the most rapidly growing segment of the population and represent 20% of all Slovak inhabitants.