Publications by authors named "Stefania Liskova"
Article Synopsis
- HER2-positive breast cancer increases the risk of central nervous system metastases, leading to leptomeningeal carcinomatosis, a severe condition with limited treatment options.
- Several case reports have explored intrathecal (i.t.) trastuzumab, often used alone or with methotrexate, in treating leptomeningeal carcinomatosis.
- This study reports successful treatment of two breast cancer patients with i.t. methotrexate and cytarabine combined with escalating doses of trastuzumab, showing good disease control and minimal side effects.
