Publications by authors named "Stefania Arlotta"
J Comp Neurol
February 2024
Article Synopsis
- Dopamine plays a key role in oxygen sensing and the regulation of ventilation in aquatic vertebrates, particularly through specialized cells in the gills known as chemoreceptive neuroepithelial cells (NECs).
- Researchers mapped the presence of tyrosine hydroxylase (TH) and dopamine transporters in zebrafish gills, indicating that dopamine is synthesized and stored in nerve terminals that interact with NECs.
- Experiments showed that manipulating dopamine receptors affects ventilation frequency during hypoxia, suggesting a feedback mechanism where D receptors on NECs help modulate the body's response to low oxygen levels.
