IOL decentration sensitivity according to spatial frequencies.

Background/aims: Investigation of the decentration sensitivity of monofocal intraocular implants with a focus on different aberration corrections depending on different spatial frequencies.

Methods: Using an optical bench, the decentration sensitivities of an intraocular lens (IOL) with a high spherical aberration correction of -0.27 µm (ZCB00 Johnson & Johnson), an IOL with an aberration correction of -0.

Rotational stability and refractive outcomes of a new hydrophobic acrylic toric intraocular lens.

Purpose: To assess rotational stability and refractive outcomes of a new toric hydrophobic acrylic intraocular lens (IOL).

Design: Single-center, prospective, interventional clinical trial.

Methods: A total of 130 eyes of 82 patients with age-related cataract and total corneal astigmatism of greater than 1.

Through-Focus Response of Extended Depth of Focus Intraocular Lenses.

Purpose: To investigate extended depth of focus intraocular lenses (EDOF IOLs), intended to extend the depth of field after cataract surgery in a comparative study at the optical bench.

Methods: An optical bench with either green or white light was used for this study. The artificial cornea used exhibited a spherical aberration of 0.

Correlation between central stromal demarcation line depth and changes in K values after corneal cross-linking (CXL).

Purpose: A stromal demarcation line (DL) after corneal cross-linking (CXL) has lately been suggested as a surrogate parameter for the success of CXL. The aim of this study was to investigate the correlation between depth of the central DL 1 month and the change in K values 12 months after CXL.

Methods: Treatment-naive subjects with keratoconus were treated using an accelerated CXL protocol [A-CXL(9*10)].

Changes in straylight and densitometry values after corneal collagen crosslinking.

Purpose: To evaluate the change in backward-directed and forward-directed corneal straylight in eyes after corneal collagen crosslinking (CXL) and its correlation with corrected distance visual acuity (CDVA) and changes in corneal topography.

Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.

Design: Retrospective cohort study.

Long-term changes in posterior chamber phakic intraocular collamer lens vaulting in myopic patients.

Objective: Evaluation of central and midperipheral vaulting of the posterior chamber phakic intraocular Collamer lens (ICL; Staar Surgical Inc., Monrovia, CA) in eyes with moderate to high myopia.

Design: Retrospective analysis of prospectively collected data.

In vitro strehl ratios with spherical, aberration-free, average, and customized spherical aberration-correcting intraocular lenses.

Purpose: To determine in vitro image qualities of artificial eyes achieved with spherical, aberration-free, average spherical aberration-correcting, and customized spherical aberration-correcting IOLs in centered, decentered, and tilted positions.

Methods: The in vitro performance of these IOL models was determined by optical bench measurements. The experimental setup included a laser light source controlled by aperture stops that corresponded to 3- and 5-mm pupil apertures, an artificial eye with three alternative corneal models exhibiting low, intermediate, and high spherical aberration (SA), IOLs mounted to an immersed IOL holder that could be moved laterally and tilted, and a charge-coupled device camera and software to determine three-dimensional point spread function (PSF), modulation transfer function, and Strehl ratio.

Intraindividual comparison of color contrast sensitivity in patients with clear and blue-light-filtering intraocular lenses.

Purpose: To evaluate the effect of blue-light-filtering intraocular lenses (IOLs) with a yellow chromophore on color contrast sensitivity by intraindividual comparison with an identically designed IOL without a blue-light filter.

Setting: Medical University of Vienna, Department of Ophthalmology, Vienna, Austria.

Methods: Randomized implantation of an AF-1 (UV) IOL (Hoya) in 1 eye and an AF-1 (UY) IOL (Hoya) in the contralateral eye was performed after phacoemulsification and primary posterior curvilinear capsulorhexis.

Depth of focus in eyes with diffractive bifocal and refractive multifocal intraocular lenses.

Purpose: To evaluate monocular and binocular depth of focus in eyes with different multifocal intraocular lens (IOLs) systems.

Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.

Methods: In this comparative interventional study, binocular implantation of multifocal IOLs was performed in 3 groups.

Contrast sensitivity function in eyes with diffractive bifocal intraocular lenses.

Purpose: To evaluate the image quality of asymmetric Acri. Twin bifocal intraocular lenses (IOLs) (Acri.Tec) by comparing distance and near black-white contrast sensitivity function with that of the Pharmacia 811E IOL.

Repeatability and reproducibility of central corneal thickness measurement with Pentacam, Orbscan, and ultrasound.

Purpose: The purpose of this study was to compare central corneal thickness (CCT) measurements obtained with a novel rotating Scheimpflug camera (Pentacam; Oculus) with scanning slit topography (Orbscan; Bausch & Lomb), and with ultrasound pachymetry (SP-2000; Tomey).

Methods: CCT in 30 healthy eyes was measured twice with each modality by 2 independent observers in random order. The results from scanning slit topography are given both with and without multiplication with the "acoustic correction factor" of 0.

Upregulation of alphavbeta6 integrin, a potent TGF-beta1 activator, and posterior capsule opacification.

Purpose: To identify the predominant activation pathway of transforming growth factor (TGF)-beta1 in the lens capsule, studying the spatial and temporal expression pattern of alphavbeta6 and thrombospondin-1. Other PCO-related proteins were also studied.

Setting: Departments of Ophthalmology and Optometrics and Clinical Pathology, Medical School, University of Vienna, Vienna, Austria.

Long-term results of implantation of phakic posterior chamber intraocular lenses.

Purpose: To study the incidence and progression of lens opacification after implantation of phakic posterior chamber intraocular lenses for myopia and its correlation with vaulting and endothelial cell density (ECD).

Setting: Department of Ophthalmology, University of Vienna Medical School, Vienna, Austria.

Methods: An implantable contact lens (ICL V4, Staar Surgical Inc.

Influence of spectacle-related changes in retinal image size on contrast sensitivity function after laser in situ keratomileusis.

Purpose: To evaluate changes in contrast sensitivity after laser in situ keratomileusis (LASIK) for the correction of myopia using a monitor-based method and considering the preoperative minification effect of high-diopter spectacles.

Setting: Department of Ophthalmology, University of Vienna Medical School, Vienna, Austria.

Methods: Fifteen eyes of 11 patients had LASIK to correct myopia.

Outcome after treatment of ametropia with implantable contact lenses.

Objective: To evaluate long-term results after insertion of implantable contact lenses (ICLs) in phakic eyes.

Design: Prospective, noncomparative, interventional case series.

Participants: Seventy-five phakic eyes (65 myopic, 10 hyperopic eyes) of 45 patients aged 21.

Glare and halo phenomena after laser in situ keratomileusis.

Purpose: To simulate and measure subjectively observed glare and halos after laser in situ keratomileusis (LASIK).

Setting: University of Vienna, Medical School, Department of Ophthalmology, Vienna, Austria.

Methods: In 16 eyes of 10 patients, the best corrected visual acuity (BCVA) and subjectively observed glare and halo size under mesopic conditions were measured before LASIK and 1, 3, and 6 months postoperatively.

Effect of tenascin and fibronectin on the migration of human corneal fibroblasts.

Purpose: To investigate the effect of fibronectin and tenascin on the migration of corneal fibroblasts.

Setting: Department of Ophthalmology, University of Vienna, Medical School, Vienna, Austria.

Methods: Using human corneal fibroblasts, a monolayer migration assay was performed to measure corneal fibroblast movement.

Comparison of visual acuities at different distances and defocus curves.

Purpose: To evaluate how visual acuities at different distances correlate with results from defocus curves.

Setting: Department of Ophthalmology and Institute of Medical Physics, University of Vienna, Medical School, Vienna, and Department of Ophthalmology, Krankenhaus St. Pölten, St.

Changes of axial length and keratometry after keratoplasty for keratoconus using the guided trephine system.

Purpose: The purpose of this study was to examine the cause of increasing myopia after penetrating keratoplasty for keratoconus with the guided trephine system.

Design: Prospective interventional study cohort.

Methods: Thirty eyes (28 patients) after keratoplasty for keratoconus were examined.

Long-term endothelial changes in phakic eyes with posterior chamber intraocular lenses.

Purpose: To evaluate the long-term endothelial cell changes in phakic eyes after implantation of a posterior chamber phakic intraocular lens to correct high ametropia.

Setting: Department of Ophthalmology, University Hospital of Vienna, Vienna, Austria.

Methods: Thirty-four eyes of 21 patients having implantation of an implantable contact lens (ICL, Staar Surgical) for high myopia or hyperopia were prospectively examined.

Quantitative performance of bifocal and multifocal intraocular lenses in a model eye: point spread function in multifocal intraocular lenses.

Objective: To compare the optical properties of bifocal diffractive and multifocal refractive intraocular lenses.

Methods: A model eye with a pupil 4.5 mm in diameter was used to determine the point spread function (PSF) of the distance focus and near focus of a diffractive bifocal intraocular lens (IOL) (model 811E; Pharmacia Inc, Columbus, Ohio) and of a refractive multifocal IOL (model SA40N; Allergan Optical Inc, Irvine, Calif) to compare them with PSFs of foci of corresponding monofocal lenses.