The coexistence of diabetes, hypertension and obesity is associated with worse pain outcomes following exercise for osteoarthritis: A cohort study on 80,893 patients.

Objectives: To investigate how the co-occurrence of diabetes, hypertension and overweight/obesity is associated with pain following an exercise intervention for knee and hip osteoarthritis (OA).

Methods: Register-based cohort study. We included people from the Swedish Osteoarthritis Register who underwent education and exercise for knee or hip OA.

Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review.

Background: Based on small to moderate effect sizes for the wide range of symptomatic treatments in osteoarthritis (OA), and on the heterogeneity of OA patients, treatment guidelines for OA have stressed the need for research on clinical predictors of response to different treatments. A meta-analysis to quantify the effect modified by the predictors using individual patient data (IPD) is suggested. The initiative to collect and analyze IPD in OA research is commenced by the OA Trial Bank.

The role of the meniscus in knee osteoarthritis: a cause or consequence?

The menisci play a critical protective role for the knee joint through shock absorption and load distribution. Asymptomatic meniscal tears are common and are frequent incidental findings on knee MR imaging of the middle-aged or older patient. A meniscal tear can lead to knee osteoarthritis (OA), but knee OA can also lead to a spontaneous meniscal tear through breakdown and weakening of meniscal structure.