Publications by authors named "Stefan J Rietmann"
Article Synopsis
- * Affected dogs exhibited significant brain degeneration and the presence of harmful autofluorescent materials in their neurons, which contributed to a preliminary diagnosis of NCL.
- * Genetic analysis identified an 18,819 base pair duplication in the MFSD8 gene in both dogs, which is linked to NCL in humans and other mammals, confirming the diagnosis as NCL7 and enabling future genetic testing to prevent breeding carriers.
Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.
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- Hypohidrotic ectodermal dysplasia is a genetic condition resulting in sparse hair, missing or malformed teeth, and issues with sweat glands, caused by mutations in an X-chromosome gene.
- A male cat was studied that displayed symptoms like complete undercoat absence and abnormal teeth, leading to a genetic examination.
- Whole-genome sequencing uncovered a specific gene variant linked to this condition, matching a known human variant, marking this as the first report of this disorder in cats.
Split paw pad disease is a scarcely defined phenotype characterized by skin lesions on the paw pads of dogs. We studied a family of German Shepherd dogs, in which four dogs developed intermittent paw pad lesions and lameness. The paw pads of two of the affected dogs were biopsied and demonstrated cleft formation in the stratum spinosum and stratum corneum, the outermost layers of the epidermis.
View Article and Find Full Text PDFThe intraruminal redox potential is stabilised by opposing influences during fermentation.
J Anim Physiol Anim Nutr (Berl)
January 2023
An optimal fermentation process in the forestomach is pivotal for the wellbeing and performance of ruminants. Complex carbohydrates are broken down into short-chain fatty acids (SCFA) which form the major energy source for the animal. A strong interrelationship of this process with intraruminal pH and redox potential (Eh) exists.
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