Publications by authors named "Stefan F Thieme"
Aim: The purpose of this prospective study was to compare the diagnostic performance of diffusion-weighted (DWI) and dynamic contrast-enhanced imaging (DCE) and volumetric analyses in the preoperative assessment of myometrial invasion in patients with endometrial carcinoma.
Materials And Methods: Thirty-five patients with endometrial cancer underwent preoperative magnetic resonance imaging including DWI and DCE for evaluation of the depth of myometrial invasion and volumetric analyses [tumor volume (TV), uterine volume (UV), tumor to volume ratio (TVR=(TV/TU)×100)]. The results of the evaluations were compared to the histopathological examinations.
Article Synopsis
- Radiofrequency ablation (RFA) is a treatment for liver tumors that can't be surgically removed; using a technique called the Pringle maneuver (PM) can help grow the size of ablations but may cause tissue damage.
- The study tested different PM techniques on porcine livers, comparing continuous PM, intermittent PM, and no PM to see how they affected the size of the ablations.
- Results showed that intermittent PM didn't reduce ablation size compared to continuous or no PM, and it even increased the ablation area when there was an initial flow before applying the PM.
Article Synopsis
- Ongoing research aims to improve the safety of radiofrequency ablation (RFA) for liver tumors using animal models, focusing on understanding the accuracy of ablation zone observations.
- The study involved performing RFA on domestic pigs' livers and analyzing the results through both photography and histological techniques, measuring cell viability in the resulting ablation zones.
- Findings revealed three distinct ablation zones with strong correlations between macro and micro-morphological data, demonstrating the ability to differentiate between non-viable (white zone) and various viable cell areas (red zones) in the liver tissue after RFA.
Value or waste: Perfusion imaging following radiofrequency ablation - early experience.
Clin Hemorheol Microcirc
June 2016
Article Synopsis
- Radiofrequency ablation (RFA) is used to treat liver tumors, but can have areas of incomplete necrosis, making immediate detection important for potential re-treatment.
- A study was conducted on healthy pig livers to compare computed tomography (CT) perfusion analysis with traditional imaging methods to assess ablative effectiveness.
- Results indicated that CT perfusion parameters could effectively differentiate necrotic tissue from healthy tissue, with significant differences noted in blood volume and flow metrics, thus highlighting the potential of CT analysis for monitoring ablation success.