How safe is minimally invasive pedicle screw placement for treatment of thoracolumbar spine fractures?

Study Design: Prospective analysis of patients who underwent minimally invasive posterior instrumentation.

Objective: The purpose of this study was to evaluate the safety of minimally invasive pedicle screw placement in patients with unstable thoracic and lumbar spine fractures using the conventional fluoroscopy technique. Although wound infection, haematoma, and new neurological deficit due to screw malplacement remain a common source of morbidity, estimates of their rates of occurrence remain relatively limited.

Cysteine-rich matricellular protein improves callus regenerate in a rabbit trauma model.

Purpose: Open fractures with severe soft-tissue trauma are predisposed to poor bone healing. The vital coupling between osteo- and angiogenesis is disturbed. Cysteine-rich protein 61 (CYR61) is an angiogenic inducer promoting vascularisation.