Increased fluvial runoff terminated inorganic aragonite precipitation on the Northwest Shelf of Australia during the early Holocene.

Inorganic precipitation of aragonite is a common process within tropical carbonate environments. Across the Northwest Shelf of Australia (NWS) such precipitates were abundant in the late Pleistocene, whereas present-day sedimentation is dominated by calcitic bioclasts. This study presents sedimentological and geochemical analyses of core data retrieved from the upper 13 meters of IODP Site U1461 that provide a high-resolution sedimentary record of the last ~15 thousand years.

[The willingness to pay for new drugs is based on ethical principles].

The County Council's board for new therapies (the NT Council) provides recommendations on the use of new drugs based on the ethical platform of priorities, founded by the Swedish parliament. The Council has formulated a policy that interprets the parliamentary ethical platform and operationalize its need and solidarity principle and cost effectiveness principle in four dimensions. The NT Council weighs the health economic evaluation of the drug and the four dimensions: the severity of the condition, the rarity of the condition, the effect size and the data reliability to determine the willingness to pay level and whether the platform allows a recommendation for using of the drug.