Monitoring Adolescent and Young Adult Patients With Cancer via a Smart T-Shirt: Prospective, Single-Cohort, Mixed Methods Feasibility Study (OncoSmartShirt Study).

Background: Wearables that measure vital parameters can be potential tools for monitoring patients at home during cancer treatment. One type of wearable is a smart T-shirt with embedded sensors. Initially, smart T-shirts were designed to aid athletes in their performance analyses.

Experiences with Wearable Sensors in Oncology during Treatment: Lessons Learned from Feasibility Research Projects in Denmark.

Background: The fraction of elderly people in the population is growing, the incidence of some cancers is increasing, and the number of available cancer treatments is evolving, causing a challenge to healthcare systems. New healthcare tools are needed, and wearable sensors could partly be potential solutions. The aim of this case report is to describe the Danish research experience with wearable sensors in oncology reporting from three oncological wearable research projects.

Feasibility of Using Wearables for Home Monitoring during Radiotherapy for Head and Neck Cancer-Results from the OncoWatch 1.0 Study.

Background: Consumer wearables allow objective health data monitoring, e.g., of physical activity and heart rate, which might change over a cancer treatment course.

Feasibility of Monitoring Patients Who Have Cancer With a Smart T-shirt: Protocol for the OncoSmartShirt Study.

Background: Studies have shown that there may be dissimilar perceptions on symptoms or side effects between patients with cancer and health care professionals. This may lead to symptomatic patients notifying the clinic irregularly or not telling the clinic at all. Wearables could help identify symptoms earlier.

Patient-reported outcome during radiotherapy for head and neck cancer: the use of different PRO questionnaires.

Purpose: Head and neck cancer (HNC) patients are typically treated with radiotherapy (RT), which might lead to side effects and deterioration of quality of life (QoL). Studies in other cancers indicate that systematic use of patient-reported outcome (PRO) can be a tool to increase awareness of patients' symptoms and improve QoL. Multiple PRO questionnaires have been developed and validated for HNC, complicating the interpretation of results from scientific studies.

Hearing Status in Survivors of Childhood Acute Myeloid Leukemia Treated With Chemotherapy Only: A NOPHO-AML Study.

Background: As more children survive acute myeloid leukemia (AML) it is increasingly important to assess possible late effects of the intensive treatment. Hearing loss has only sporadically been reported in survivors of childhood AML. We assessed hearing status in survivors of childhood AML treated with chemotherapy alone according to 3 consecutive NOPHO-AML trials.

The Acceptable Noise Level and the Pure-Tone Audiogram.

Purpose: The vast majority of previous studies suggest that there is no relationship between the acceptable noise level (ANL) and pure-tone hearing thresholds reported as the average pure-tone hearing thresholds (pure-tone average). This study aims to explore (a) the relationship between hearing thresholds at individual frequencies and the ANL and (b) a measure of the slope of the audiogram and ANL.

Method: Sixty-three Danish adult hearing aid users participated.

Objective and Subjective Outcome of a New Transcutaneous Bone Conduction Hearing Device: Half-year Follow-up of the First 12 Nordic Implantations.

Objective: To examine the objective and subjective outcome of a new transcutaneous bone conduction hearing device.

Study Design: Prospective, consecutive case series.

Patients: Twelve patients were implanted.

The effect of repeated measurements and working memory on the most comfortable level in the ANL test.

Objective: To study the effect of a large number of repetitions on the most comfortable level (MCL) when doing the acceptable noise level (ANL) test, and explore if MCL variability is related to central cognitive processes.

Design: Twelve MCL repetitions were measured within the ANL test using interleaved methodology during one session using a non-semantic version. Phonological (PWM) and visuospatial working memory (VSWM) was measured.

Prediction of IOI-HA scores using speech reception thresholds and speech discrimination scores in quiet.

Background: Outcome measures can be used to improve the quality of the rehabilitation by identifying and understanding which variables influence the outcome. This information can be used to improve outcomes for clients. In clinical practice, pure-tone audiometry, speech reception thresholds (SRTs), and speech discrimination scores (SDSs) in quiet or in noise are common assessments made prior to hearing aid (HA) fittings.

Does the acceptable noise level (ANL) predict hearing-aid use?

Objective: It has been suggested that individuals have an inherent acceptance of noise in the presence of speech, and that different acceptance of noise results in different hearing-aid (HA) use. The acceptable noise level (ANL) has been proposed for measurement of this property. It has been claimed that the ANL magnitude can predict hearing-aid use patterns.

The acceptable noise level: the effect of repeated measurements.

Objective: This study explores if increasing number of repetitions might improve the precision of the acceptable noise level (ANL) test.

Design: We measured twelve ANL repetitions, i.e.

Carbon, land, and water footprint accounts for the European Union: consumption, production, and displacements through international trade.

A nation's consumption of goods and services causes various environmental pressures all over the world due to international trade. We use a multiregional input-output model to assess three kinds of environmental footprints for the member states of the European Union. Footprints are indicators that take the consumer responsibility approach to account for the total direct and indirect effects of a product or consumption activity.

Acceptable noise level (ANL) with Danish and non-semantic speech materials in adult hearing-aid users.

Objective: The acceptable noise level (ANL) test is used for quantification of the amount of background noise subjects accept when listening to speech. This study investigates Danish hearing-aid users' ANL performance using Danish and non-semantic speech signals, the repeatability of ANL, and the association between ANL and outcome of the international outcome inventory for hearing aids (IOI-HA).

Design: ANL was measured in three conditions in both ears at two test sessions.

Acceptable noise level: repeatability with Danish and non-semantic speech materials for adults with normal hearing.

Objective: The acceptable noise level (ANL) is used to quantify the amount of background noise that subjects can accept while listening to speech, and is suggested for prediction of individual hearing-aid use. The aim of this study was to assess the repeatability of the ANL measured in normal-hearing subjects using running Danish and non-semantic speech materials as stimuli and modulated speech-spectrum and multi-talker babble noises as competing stimuli.

Design: ANL was measured in both ears at two test sessions separated by a period ranging from 12 to 77 days.

Evaluation of long-term patient satisfaction and experience with the Baha® bone conduction implant.

Objective: Evaluate long-term patient satisfaction with bone-anchored hearing aids (the Baha®, now referred to by Cochlear as a 'bone conduction implant') in our hospital clinic spanning the eighteen-year period from the inception of our Baha program. The researchers further wished to analyse the various factors leading to patient satisfaction/dissatisfaction with their Baha. We developed a new questionnaire to obtain a comprehensive impression of individual patient practices, general satisfaction, and experiences with their Baha in respect to time spent using Baha, sound quality, annoyance from noise disturbance, ease of communication, cosmetic appearance, and satisfaction with the Baha amongst patient relatives, an aspect not previously investigated.

Acceptable noise level with Danish, Swedish, and non-semantic speech materials.

Objective: Acceptable noise level (ANL) has been established as a method to quantify the acceptance of background noise while listening to speech presented at the most comfortable level. The aim of the present study was to generate Danish, Swedish, and a non-semantic version of the ANL test and investigate normal-hearing Danish and Swedish subjects' performance on these tests.

Design: ANL was measured using Danish and Swedish running speech with two different noises: Speech-weighted amplitude-modulated noise, and multitalker speech babble.

Comparison of two bone anchored hearing instruments: BP100 and Ponto Pro.

Objective: This study aimed at investigating if there were differences in auditory performance, operation, or user preference between the Ponto Pro or the BP100, two bone anchored hearing instruments (BAHI) with modern sound processing technology.

Design: Subjects wore the devices in daily life in a crossover study for periods ranging from 25 to 63 days. A speech-in-noise test was carried out as well as measures of noise reduction and feedback suppression algorithms.

The McKenzie method compared with manipulation when used adjunctive to information and advice in low back pain patients presenting with centralization or peripheralization: a randomized controlled trial.

Study Design: Randomized controlled trial.

Objective: To compare the effects of the McKenzie method performed by certified therapists with spinal manipulation performed by chiropractors when used adjunctive to information and advice.

Summary Of Background Data: Recent guidelines recommend a structured exercise program tailored to the individual patient as well as manual therapy for the treatment of persistent low back pain.

Simulated real-ear measurements of benefit from digital feedback suppression.

Digital feedback suppression (DFS) enables users of hearing instruments (HI) to benefit from amplification levels that normally would provoke whistling or poor sound quality. A standardized test for the measurement of DFS benefit is not available. This paper proposes and evaluates an objective method for assessment of extra feedback-free amplification (headroom) provided by a given DFS.

Real-ear measurement verification for open, non-occluding hearing instruments.

Real-ear measurements using the modified pressure method with concurrent (real-time) equalization can be inaccurate, when amplified sound leaks out of the ear canal and reaches the reference microphone. In such situations the reference microphone will detect an increased sound level and reduce the output of the loudspeaker to maintain the desired level. The risk of having errors due to leaks increases if digital feedback suppression (DFS) is used, thus achieving higher feedback-free gain levels.

Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training.

The present study investigated the influence of creatine and protein supplementation on satellite cell frequency and number of myonuclei in human skeletal muscle during 16 weeks of heavy-resistance training. In a double-blinded design 32 healthy, male subjects (19-26 years) were assigned to strength training (STR) while receiving a timed intake of creatine (STR-CRE) (n=9), protein (STR-PRO) (n=8) or placebo (STR-CON) (n=8), or serving as a non-training control group (CON) (n=7). Supplementation was given daily (STR-CRE: 6-24 g creatine monohydrate, STR-PRO: 20 g protein, STR-CON: placebo).

Learning effect when using the Danish Hagerman sentences (Dantale II) to determine speech reception threshold.

The objective of the present study was to examine the learning effect found when using the Danish sentence test, Dantale II, in our daily clinical work. Specifically, the aim was to determine the within-visit and the inter-visit learning effects when the Dantale II is presented to aided hearing-impaired listeners who have not previously completed the task. Nineteen subjects participated in the study.

The behaviour of satellite cells in response to exercise: what have we learned from human studies?

Understanding the complex role played by satellite cells in the adaptive response to exercise in human skeletal muscle has just begun. The development of reliable markers for the identification of satellite cell status (quiescence/activation/proliferation) is an important step towards the understanding of satellite cell behaviour in exercised human muscles. It is hypothesised currently that exercise in humans can induce (1) the activation of satellite cells without proliferation, (2) proliferation and withdrawal from differentiation, (3) proliferation and differentiation to provide myonuclei and (4) proliferation and differentiation to generate new muscle fibres or to repair segmental fibre injuries.