Publications by authors named "Stayner R"
Article Synopsis
- About 100 million Americans live with chronic pain, and while opioids are commonly prescribed for treatment, their misuse is a growing nationwide issue.
- Laws and standards governing opioid prescribing are frequently updated, with initiatives like the National Drug Control Policy and various state prescription monitoring programs in place to manage prescription drug abuse.
- Balancing the need for effective pain treatment with the prevention of prescription drug abuse is crucial, and healthcare providers must stay informed about evolving regulations to ensure patient safety and care.
The genetic addition of hexahistidine (H(6)) tags is widely used to isolate recombinant proteins by immobilized metal-affinity chromatography (IMAC). Addition of a tyrosine residue to H(6) tags enabled proteins to be covalently cross-linked under mild conditions in a manner similar to the natural, site-specific cross-linking of tyrosines into dityrosine. A series of seven hexahistidine tags with tyrosines placed in various positions (H(6)Y tags) were added to the amino terminus of the I28 immunoglobulin domain of the human cardiac titin.
View Article and Find Full Text PDFThe overall comfort of four current production tractor seats and some individual features of seat design have been assessed by a method of paired comparisons. The experiment was carried out under both static and dynamic conditions and subjects had to adopt natural postures similar to those adopted when ploughing. The results suggest that operators can differentiate seat comfort differences reliably.
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