An Experimental Comparison of In-Person and Remote Instruction for Preschoolers with Disabilities.

Remote instruction is becoming increasingly common, yet few studies have directly compared remote and in-person instruction in a controlled manner. We used a reversal design to compare the effects of in-person and remote instruction for six preschool participants with disabilities learning tacts and sight words. Distribution of instruction, methodology, and materials across in-person and remote conditions were equated so that the only difference across conditions was the modality of instruction.

Familial Alzheimer disease among Caribbean Hispanics: a reexamination of its association with APOE.

Objectives: To reexamine the association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and familial Alzheimer disease (AD), and to search for novel genes that may be associated with susceptibility in Caribbean Hispanic families with a history of AD.

Methods: Families were identified in Caribbean Hispanic communities in the greater New York City area, the Dominican Republic, and Puerto Rico. Each family in the study cohort included at least 2 living relatives with a history of dementia.