Vitamin B6 versus mianserin and placebo in acute neuroleptic-induced akathisia: a randomized, double-blind, controlled study.

Treatment strategies against acute neuroleptic-induced akathisia (NIA) include anticholinergic (antimuscarinic) agents, dopamine agonists, GABAergic agents, beta-blockers, benzodiazepines, and serotonin antagonists. However, many patients who have acute akathisia fail to respond. In previous studies, mianserin and vitamin B6 were found to be effective in the treatment of acute akathisia.

Vitamin B6 treatment in acute neuroleptic-induced akathisia: a randomized, double-blind, placebo-controlled study.

Background: Treatment strategies for acute neuroleptic-induced akathisia (NIA) contain anticholinergic (antimuscarinic) agents, dopamine agonists, gamma-aminobutyric acid (GABA)-ergic agents, beta-blockers, benzodiazepines, and serotonin antagonists. Nevertheless, many patients who suffer from acute akathisia fail to respond to treatment. In earlier studies, vitamin B6 was found to be effective in the treatment of neuroleptic-induced movement disorders.

[The structure of neuropsychic disorders in the workers of a large industrial enterprise].

The structure of neuropsychic and psychosomatic disorders was examined in workers of a large electrotechnical enterprise. Screening methods were used in the form of two questionnaires: screening of patients of the ambulatory Department of the Leningrad Research Institute of Neurology and Psychiatry as well as a multipurpose questionnaire for screening worked out at the Chair of Psychiatry, medical Psychology and Narcology of the Donetsk Medical Institute. Results of the study are described.