Publications by authors named "Starlyn L Okada-Rising"
J Transl Med
February 2024
Article Synopsis
- Targeted drug delivery to mitochondria shows promise for treating traumatic brain injury (TBI) in military and civilian populations but faces challenges from the blood-brain barrier (BBB).
- Traditional methods like intraventricular and intraparenchymal delivery are invasive and can fail to adequately expose affected brain areas due to cerebrospinal fluid turnover.
- An emerging approach of direct intranasal drug delivery is non-invasive, effectively bypasses the BBB, and has demonstrated success in animal models for various CNS disorders, prompting discussions on its advantages and relevant drug compounds for future research.
