The effect of nasally administered budesonide respules on adrenal cortex function in patients with chronic rhinosinusitis.

Objectives: To evaluate whether nasal administration of budesonide in adults with chronic rhinosinusitis for 30 days suppresses adrenal function and to assess its clinical efficacy.

Design: An open-label prospective study.

Setting: Academic medical center.

Chronic rhinosinusitis patients with polyps or polypoid mucosa have a greater burden of illness.

Background: Recent studies suggest chronic rhinosinusitis without nasal polyposis (CRSsNP) and CRS with nasal polyposis (CRScNP) represent distinct pathological entities. The aim of this study was to determine whether patients with CRSsNP, CRScNP, and polypoid CRS could be distinguished by clinical features, radiologic extent of disease or use of medications.

Methods: New patients with CRS (n = 126) were enrolled in a prospective outcomes study.

Clinical outcomes of chronic rhinosinusitis in response to medical therapy: results of a prospective study.

Background: Little information exists regarding the outcome of medical management of chronic rhinosinusitis (CRS) in adults. The aim of this study was to examine whether baseline patient demographics, symptoms, objective findings, or treatment strategies were associated with improved CRS outcomes over time.

Methods: Eighty-four new patients with CRS were evaluated and medically treated for up to 12 months.

The otolaryngologist-ophthalmologist relationship: an historic perspective.

Otolaryngology and ophthalmology have a long and congenial professional relationship in the development of their mutual specialties over many years. In the early years they were one professional society, but later split into their separate specialties. Some problems involve both specialties because of the shared common anatomic areas.