Extracts from Wheat, Maize, and Sunflower Waste as Natural Raw Materials for Cosmetics: Value-Added Products Reaching Sustainability Goals.

Agricultural waste is underutilized, and sometimes burning them has a negative impact on the environment and human health. This research investigates the untapped potential of extracts from maize, wheat and sunflower waste as natural materials for cutaneous, specifically, cosmetic application. The possibility of incorporating lipid and ethanol extracts from wheat, maize, and sunflower into creams was investigated together with their potential contribution to the structural and functional properties of the topical formulations.

Synthesis and Antimicrobial Activity of Newly Synthesized Nicotinamides.

Antioxidants are promising compounds with antimicrobial activity against drug-resistant pathogens, especially when combined with conventional antimicrobials. Our study aimed to characterize the structure of nicotinamides synthesized from nicotinic acid and thiocarbohydrazones and to evaluate their antibacterial and antifungal activity. Seven nicotinic acid hydrazides (NC -) were synthesized using mono-thiocarbohydrazones with hydroxyl group substituents, along with quinolone, phenolic, and pyridine rings known for their antimicrobial activity.

Omentomyelopexy for the Treatment of a Persistent Lumbar Pseudomeningocele: A Case Report With Technical Note.

Background And Importance: Pseudomeningoceles are extradural accumulations of cerebrospinal fluid. In most cases, they appear as a complication of spinal operations. Omentomyelopexy is a surgery in which an autologous omentum flap is implanted over the dural opening.

High-dose-rate Brachytherapy Monotherapy in Patients With Localised Prostate Cancer: Dose Modelling and Optimisation Using Computer Algorithms.

Aims: Interstitial high-dose-rate brachytherapy (HDR-BT) is an effective therapy modality for patients with localized prostate carcinoma. The objectives of the study were to optimise the therapy regime variables using two models: response surface methodology (RSM) and artificial neural network (ANN).

Materials And Methods: Thirty-one studies with 5651 patients were included (2078 patients presented as low-risk, 3077 patients with intermediate-risk, and 496 patients with high-risk).

Robust Finger Interactions with COTS Smartwatches via Unsupervised Siamese Adaptation.

Wearable devices like smartwatches and smart wristbands have gained substantial popularity in recent years. However, their small interfaces create inconvenience and limit computing functionality. To fill this gap, we propose ViWatch, which enables robust finger interactions under deployment variations, and relies on a single IMU sensor that is ubiquitous in COTS smartwatches.

Beneath the surface: Decoding the impact of Chironomus riparius bioturbation on microplastic dispersion in sedimentary matrix.

A detailed understanding of microplastics (MPs) behaviour in freshwater ecosystems is crucial for a proper ecological assessment. This includes the identification of significant transport pathways and net accumulation zones, considering their inherent, and already proven influence on aquatic ecosystems. Bioavailability of toxic agents is significantly influenced by macroinvertebrates' behaviour, such as bioturbation and burrowing, and their prior exposure history.

Analysis of Lower Extremity Amputations from the SerbVasc Registry.

Background: Peripheral arterial disease (PAD) and diabetes are the major causes of lower extremity amputations (LEAs) worldwide. Morbidity and mortality in patients with LEAs are high with an associated significant burden on the global health system. The aim of this article is to report the overall morbidity and mortality rates after major and minor LEAs from the Serbian Vascular Registry (SerbVasc), with an analysis of predictive factors that influenced adverse outcomes.

Copeptin levels increase in response to both insulin-induced hypoglycemia and arginine but not to clonidine: data from GH-stimulation tests.

Background: The diagnosis of the polyuria-polydipsia syndrome is challenging. Copeptin is a robust biomarker of arginine vasopressin (AVP) secretion. Arginine, which stimulates growth hormone (GH), has been shown also to stimulate copeptin secretion via unknown mechanisms.

Antifungal Activity of Essential Oil against : Time-Kill Study on Pediatric Sputum Isolates.

The aim of our study was to determine the susceptibility of 15 sputum isolates on fluconazole and caspofungin, as well as the antifungal potential of essential oil (LAEO). The commercial LAEO was analyzed using gas chromatography-mass spectrometry. The antifungal activity was evaluated using EUCAST protocol.

VoiceCare: A Voice-Interactive Cognitive Assistant on a Smartwatch for Monitoring and Assisting Daily Healthcare Activities.

Following several health activities in daily life (e.g., medication/exercise plans, handwashing, physiological monitoring) properly often requires monitoring and assistance support.

A Multimodal Framework for Robustly Distinguishing among Similar Emotions using Wearable Sensors.

Detecting the correct emotion is crucial for improved mental health outcomes. While the existing works on emotion recognition focus on detecting the common or primary emotions only, there exists some uncommon or secondary emotions of similar kind (e.g.

Effects of a microplastic mixture differ across trophic levels and taxa in a freshwater food web: In situ mesocosm experiment.

The ubiquitous presence of microplastics (MP) in aquatic ecosystems can affect organisms and communities in multiple ways. While MP research on aquatic organisms has primarily focused on marine ecosystems and laboratory experiments, the community-level effects of MP in freshwaters, especially in lakes, are poorly understood. To examine the impact of MP on freshwater lake ecosystems, we conducted the first in situ community-level mesocosm experiment testing the effects of MP on a model food web with zooplankton as main herbivores, odonate larvae as predators, and chironomid larvae as detritivores for seven weeks.

Validity and Feasibility of the Monitoring and Modeling Family Eating Dynamics System to Automatically Detect In-field Family Eating Behavior: Observational Study.

Background: The field of dietary assessment has a long history, marked by both controversies and advances. Emerging technologies may be a potential solution to address the limitations of self-report dietary assessment methods. The Monitoring and Modeling Family Eating Dynamics (M2FED) study uses wrist-worn smartwatches to automatically detect real-time eating activity in the field.

Alteration of Oxidative stress and apoptotic markers alterations in the rat prefrontal cortex influence behavioral response induced by cisplatin and N-acetylcysteine in the tail suspension test.

Cisplatin therapy is often accompanied by neurotoxicity manifestation, and since the prefrontal cortex is strongly involved in emotion regulation, the aim of this study was to analyze the alterations in the oxidative and apoptotic status of this brain region, with its behavioral impact in rats, following cisplatin administration, with or without N-acetylcysteine supplementation. Thirty-two male Wistar albino rats were randomly divided into four equal experimental groups: control, cisplatin group (single dose of 7.5 mg/kg, intraperitoneally (i.

The empirical formula for calculating the incident air Kerma in intraoral radiographic imaging.

Objectives: The aim of this paper is to determine the empirical formula for calculating the incident air kerma (Ki), used as a patient dose descriptor in the intraoral radiographic imaging.

Methods: The data for the formula were collected during the regular annual inspection of intraoral dental X-ray units in 2018, 2019 and early 2020. The measurement data of 50 X-ray units were processed to develop the formula.

In Situ Effects of a Microplastic Mixture on the Community Structure of Benthic Macroinvertebrates in a Freshwater Pond.

Benthic communities contain some of the most threatened organisms in aquatic habitats due to different anthropogenic pressures. The high abundance of microplastics in sediments will continue to increase in the future, further increasing the probability of interactions between macroinvertebrates and microplastics. In the present study, a benthic community in a relatively pristine shallow pond was exposed either to an environmentally relevant high concentration of a microplastic mixture of 80 g m in the sediment, or a control sediment, without the addition of microplastics.

An integrated approach of PCA and PROMETHEE in spatial assessment of circular economy indicators.

In order to ensure environmental sustainability, reducing the consumption of renewable resources, finding adequate substitutes for non-renewable resources, and reducing the generation of waste and pollution are necessities. The concept of circular economy one of the possible and good responses to improve the sustainability of the system, as it places particular emphasis on the reduction, reutilization and recycling of its elements. The paper presents a comparative analysis of the circular economy development in European Union countries based on the dataset encompasses 11 indicators, covering the seven-year period with biennial data.

Patients and experiences from the first Danish flavour clinic.

Introduction: Chemosensory dysfunction is common. Although patients complain of taste loss, the most common cause of a diminished taste experience is olfactory dysfunction.

Methods: Since January 2017, patients with complaints about smell and/or taste loss have been referred to the Flavour Clinic by ear, nose and throat (ENT) practitioners.

Smarthealth technology study protocol to improve relationships between older adults with dementia and family caregivers.

Aim: The aim of this study is to develop a Smarthealth system of monitoring, modelling, and interactive recommendation solutions (for caregivers) for in-home dementia patient care that focuses on caregiver-patient relationships.

Design: This descriptive study employs a single-group, non-randomized trial to examine functionality, effectiveness, feasibility, and acceptability of the novel Smarthealth system.

Methods: Thirty persons with Alzheimer's Disease or related dementia and their family caregivers (N = 30 dyads) will receive and install Smarthealth technology in their home.

Food preferences, food neophobia and chemosensation among adolescents with ADHD.

Aim: It has been suggested that adolescents diagnosed with ADHD have an unhealthier diet compared to their peers without ADHD. The association between chemosensation (smell and taste) and dietary patterns remains unknown. The aim is to investigate unhealthy food preferences and food neophobic behaviour among adolescents diagnosed with ADHD.

iWash: A smartwatch handwashing quality assessment and reminder system with real-time feedback in the context of infectious disease.

Washing hands properly and frequently is the simplest and most cost-effective interventions to prevent the spread of infectious diseases. People are often ignorant about proper handwashing in different situations and do not know if they wash hands properly. Smartwatches are found to be effective for assessing the quality of handwashing.

[Copeptin is a new diagnostic biomarker for diabetes insipidus].

Differential diagnosis of diabetes insipidus is challenging. The water deprivation test is the current gold standard, but the test is cumbersome, and the diagnostic performance is poor. Copeptin, which is a split product of the vasopressin pre-propeptide, appears to be a robust biomarker in the circulation and a promising tool for the diagnosis of patients with polyuria and polydipsia, especially when measured in conjunction with intravenous infusion of arginine, as summarised in this review.

Extracts Promote Doxorubicin Effects against Lung Adenocarcinoma Cells In Vitro.

and its secondary metabolites have been shown to have anticancer potential. We performed MTT, scratch, and colony formation assays; analyzed cell cycle phase distribution and doxorubicin uptake and retention with flow cytometry; and detected alterations in the expression of genes involved in the formation of cell-cell interactions and migration using quantitative real-time PCR following treatment of lung adenocarcinoma cells with doxorubicin, extracts, or their combination. MTT assay results suggested strong synergistic effects of the combined treatments, and their application led to an increase in cell numbers in the subG1 phase of the cell cycle.

Modelling and optimisation of treatment parameters in high-dose-rate mono brachytherapy for localised prostate carcinoma using a multilayer artificial neural network and a genetic algorithm: Pilot study.

Background: High-dose-rate mono brachytherapy (HDR-MB) is employed in the treatment of prostate carcinoma (CaP). As an ideal plan of CaP brachytherapy cannot be created, it is necessary to identify a reliable tool to optimise the parameters of HDR-MB. This paper applies a multilayer artificial neural network (MANN) and a genetic algorithm (GA) to optimise brachytherapy parameters based on an individual dose-volumetric analysis.

Antioxidant Supplementation in the Treatment of Neurotoxicity Induced by Platinum-Based Chemotherapeutics-A Review.

Cancer represents one of the most pernicious public health problems with a high mortality rate among patients worldwide. Chemotherapy is one of the major therapeutic approaches for the treatment of various malignancies. Platinum-based drugs (cisplatin, oxaliplatin, carboplatin, etc.