Publications by authors named "Stanislav Adamec"
Article Synopsis
- The study examines the relationship between antithrombotic (AT) therapy and outcomes for patients with upper gastrointestinal bleeding (UGB) in a hospital setting.
- It found that prior AT treatment did not lead to worse in-hospital outcomes, but the occurrence of haemorrhagic shock significantly worsened survival chances.
- After a bleeding event, about 73.8% of patients were able to safely restart their AT therapy, with higher mortality after six months linked to older age, comorbidities, liver cirrhosis, and a history of cancer.
Aim: To evaluate the frequency of the loss of the Adenomatous Polyposis Coli (APC) protein and to compare the APC status with the characteristics of colorectal adenomas.
Methods: Immunohistochemical analysis of the APC protein was performed on 118 adenomas and the results were compared with parameters of malignant potential, location of adenomas, macroscopic appearance and age of the patients.
Results: A complete loss of the APC protein was found in 28 (24%) adenomas, while 90 (76%) were APC positive.