Situs anomalies, including situs inversus and situs ambiguous (SAMB), are rare congenital conditions typically noted in pediatric populations, with SAMB being particularly uncommon in adults. This case study addresses the incidental discovery of situs ambiguous with polysplenia in a 65-year-old man evaluated for suspected adrenal adenoma. The patient's medical history included benign prostatic hyperplasia and tuberculous pleurisy.
View Article and Find Full Text PDFBreast cancer is the most prevalent cancer worldwide, affecting both low- and middle-income countries, with a growing number of cases. In 2024, about 310,720 women in the U.S.
View Article and Find Full Text PDFAim: There is a lack of multidisciplinary studies examining the link between psychological factors and glycemic control in individuals with chronic illnesses. The aim of this study is to investigate the relationship between psychological factors such as resilience, perceived stress, emotional regulation, aggressiveness, and glycated hemoglobin (HbA1c) levels in patients with type 2 diabetes. Additionally, the study seeks to determine the predictive value of perceived stress and resilience on HbA1c levels and to explore the role of anger expression and emotion regulation strategies in glycemic control, comparing diabetic patients to healthy controls.
View Article and Find Full Text PDFThe transition from the current linear model of abstraction, use and discharge of water into recycle-reuse under the circular economy (CE) principles is momentous. An analysis of recent literature about the economic impact of linear to circular (L2C) transition is made. The review investigates the economic implications (i.
View Article and Find Full Text PDFThis paper presents a novel development of sludge cellulose plastic composite (SPC) in line with the circular economy concept by using recovered sludge cellulose from wastewater treatment plant (WWTP). Bearing the aim of replacing the wood in wood plastic composite (WPC) with sludge cellulose, WPC was developed in parallel for determining the substitution potentials. In order to maximise the integration of properties, maleic anhydride (MA) and vinyltrimethoxysilane (VTMS) coupling agents were employed to refine the interfacial bonding of both SPC and WPC.
View Article and Find Full Text PDFBackground: The glucagon-like peptide-1 (GLP-1) and the glucose- dependent Insulinotropic peptide (GIP) are natural incretin hormones, which are secreted respectively by the L- and K-cells of the intestinal mucosa in response to the physiological gastrointestinal glucose absorption. In patients with type 2 diabetes mellitus, the incretin effect is reduced, whereas the results in type 1 diabetes mellitus (T1DM) are heterogeneous, in some patients normal incretin response is observed.
Aim: Comparative analysis of the basal serum levels of the incretin hormones GLP-1 and GIP in patients with type 1 DM and in individuals without carbohydrate disorders.
Direct nitrous oxide (NO) emissions during the biological nitrogen removal (BNR) processes can significantly increase the carbon footprint of wastewater treatment plant (WWTP) operations. Recent onsite measurement of NO emissions at WWTPs have been used as an alternative to the controversial theoretical methods for the NO calculation. The full-scale NO monitoring campaigns help to expand our knowledge on the NO production pathways and the triggering operational conditions of processes.
View Article and Find Full Text PDFBackground: The reproducibility of echocardiographic measurements of myocardial strain, performed in a community-based setting, has not been reported previously.
Methods: The reproducibility of left ventricular strain measurements was examined in two samples of 20 participants each from the Offspring Cohort of the Framingham Heart Study (mean age, 63 ± 9 years; 59% women). Two-dimensional speckle-tracking-based measurements of global peak left ventricular strain in systole were performed in the apical four-chamber, apical two-chamber, and midventricular parasternal short-axis views.
Background: There is rapidly growing interest in applying measures of myocardial strain and synchrony in clinical investigations and in practice; data are limited regarding their reference ranges in healthy individuals.
Methods And Results: We performed speckle-tracking-based echocardiographic measures of left ventricular myocardial strain and synchrony in healthy adults (n=739, mean age 63 years, 64% women) without cardiovascular disease. Reference values were estimated using quantile regression.
The results of several studies have shown that homosexual men have an increased prevalence of non-right-handedness and atypical patterns of hemispheric functional asymmetry. Non-right-handedness in men has been associated with increased size of the corpus callosum (CC), particularly of the isthmus, which is the posterior region of the callosal body connecting parietotemporal cortical regions. We hypothesized that isthmal area would be greater in homosexual men, even among right handers.
View Article and Find Full Text PDFBackground: Recent studies have reported significant atrophy of the corpus callosum (CC) in Alzheimer's Disease (AD). However, it is currently unknown whether CC atrophy is associated with specific cortical volume changes in AD. Moreover, possible atrophy in extra-callosal commissures has not been examined to date.
View Article and Find Full Text PDFWe determined topographic selectivity and diagnostic utility of brain atrophy in probable Alzheimer's disease (AD) and correlations with demographic factors such as age, sex, and education. Computerized imaging analysis techniques were applied to MR images in 32 patients with probable AD and 20 age- and sex-matched normal control subjects using tissue segmentation and three-dimensional surface rendering to obtain individualized lobar volumes, corrected for head size by a residualization technique. Group differences emerged in gray and white matter compartments particularly in parietal and temporal lobes.
View Article and Find Full Text PDFMonte Carlo simulations were performed to determine whether the multicomponent T2 distribution of tissue can be estimated accurately from T2 decay data acquired in vivo. Simulated data were generated for white matter, fast twitch muscle, and breast tissue. The signal-to-noise ratio, number of data samples, and minimum echo time were varied from the experimental conditions currently achievable with MRI to those achievable for in vitro experiments.
View Article and Find Full Text PDFMR imaging at 1.5 T was used to investigate variations in breast parenchyma during the menstrual cycle. Seven subjects were examined twice weekly over at least one menstrual cycle.
View Article and Find Full Text PDFJ Magn Reson Imaging
May 1995
The authors have developed a method for reducing magnetic resonance (MR) image artifacts caused by planar motion. Segments of k-space acquired with the subject stationary are detected automatically. Each k-space segment is Fourier transformed into an image in which rotational and translational displacements are measured manually.
View Article and Find Full Text PDFTo determine the influence of collagen orientation on the magnetic resonance (MR) imaging appearance of articular cartilage, spin-echo MR images of normal bovine patellar specimens were obtained with the specimens rotated in 5 degrees increments between +75 degrees and -130 degrees. Hyperintense superficial, hypointense middle, and intermediate-intensity deep laminae were observed. Results of polarized light microscopy of histologic specimens confirmed the three zones, and transmission electron microscopy showed different collagen arrangements in the zones.
View Article and Find Full Text PDFThe distribution of alpha- and beta-type receptors for PDGF was studied immunohistochemically in the uterus of cycling and pregnant pigs with well-documented hormonal status in order to determine a possible steroid hormone-dependence of its expression. Peroxidase-antiperoxidase (PAP) labelling at light microscopical level was done with rabbit polyclonal antisera recognizing either both alpha- and beta-type receptors (PDGFR-1), or selectively beta-type (PDGFR-3). Immunoreactivity to the PDGF-receptors of alpha- and beta-type (PDGFR-1) was present in all endometrial samples examined, being located principally on subepithelial stromal and endothelial cells, the wall of endometrial blood vessels and in the fetal placenta (trophoblast and adjoining blood capillaries).
View Article and Find Full Text PDFThe present study aimed to correlate the repeat breeder syndrome in the bovine with an impaired or suboptimal uterine progestational response. Concentrations of nuclear (i.e.
View Article and Find Full Text PDFThe acute effects of oestradiol-17 beta on the expression of the oestrogen receptor (ER) and insulin-like growth factor I (IGF-I) in the endometrium of ovariectomized pigs were examined. The steroid receptor level was assayed by hormone binding techniques and specific mRNAs analyzed by solution hybridization using 35S-labelled RNA probes complementary to the ligand-binding domain of the ER receptor gene and a 160 bp PanI-Pvul fragment of the IGF-I gene. One hour after a single injection of oestradiol (1 micrograms/kg BW), the nuclear oestrogen receptor (ERn) mean level was increased 3-fold whereas the ER mRNA content had not changed significantly.
View Article and Find Full Text PDFThe present study establishes and validates an in vitro binding and exchange assay for tissue receptors for oestradiol (E) and progesterone (P) in pig uterus. Both hormones bound to specific cytoplasmic (Rc) and nuclear (Rn) receptor proteins with high affinity. The relative concentrations of the receptors were measured in dissected samples from endometrium and myometrium obtained at late prooestrus, oestrus, and luteal phases of the oestrous cycle.
View Article and Find Full Text PDFLH/hCG-binding sites were measured in crude membrane fractions of porcine uteri. Specific high affinity and low capacity receptors for LH/hCG were found in all (n = 17) membrane preparations of myometrium but in only 5 of 17 crude membrane fractions of endometrium of porcine uteri. There was very little competition between hCG and porcine GH (pGH), bovine TSH, pFSH, and pPRL (0.
View Article and Find Full Text PDFThe effects of copper deficiency on the fatty acid composition of mitochondrial and microsomal phospholipids in rat liver were studied. Copper deficiency was induced by a milk powder diet. To evaluate the effect of the milk diet on the fatty acid pattern of mitochondrial and microsomal phospholipids, one group of rats was fed Cusupplemented powdered milk.
View Article and Find Full Text PDFJ Steroid Biochem
January 1985
The concentrations of the tissue receptors for oestradiol (E) and progesterone (P) in the porcine oviduct at different stages on the oestrous cycle have been investigated by in vitro binding and exchange methods. Both hormones bound to specific cytoplasmic (Rc) and nuclear (Rn) receptor proteins with high affinity. The concentrations of ERc and ERn were two-fold higher in the ampulla as compared to the isthmus.
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