Endothelial dysfunction in patients with systemic sclerosis.

Introduction: Patients with systemic sclerosis experience endothelial dysfunction and damage even in the absence of clinical manifestations.

Aim: To evaluate various methods for assessing the endothelial function for their applicability to clinical practice.

Material And Methods: Forty-two patients (7 men and 35 women) with systemic sclerosis and 36 controls (11 men and 25 women) matched for age, sex, body mass index, smoking habit, and comorbidities were enrolled in the study.

Endothelial dysfunction in patients with eosinophilic granulomatosis with polyangiitis.

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis associated with asthma and eosinophilia. Endothelial dysfunction has been well documented in other types of vasculitis but not in EGPA. Thirty patients (10 men and 20 women) diagnosed with EGPA and remaining in a remission, and 58 controls (24 men and 34 women) matched for age, sex, and body mass index, were enrolled in the study.

Endothelial dysfunction in patients with granulomatosis with polyangiitis: a case-control study.

Background: Granulomatosis with polyangiitis (GPA) is a rare granulomatous vasculitis affecting small- and medium-sized blood vessels. In optimally treated patients with long-standing disease, the common cause of death is atherosclerosis even in the absence of typical risk factors.

Objective: To evaluate endothelial dysfunction in GPA patients.