Publications by authors named "Stamatios Kokkinakis"

Introduction: Predicted 1-year survival of children with trisomy 18 (T18) has increased to 59.3%. We aimed to systematically review the characteristics, management, and outcomes of children with T18 and hepatoblastoma.

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Colorectal liver metastasis (CRLM) is a disease entity that warrants special attention due to its high frequency and potential curability. Identification of "high-risk" patients is increasingly popular for risk stratification and personalization of the management pathway. Traditional regression-based methods have been used to derive prediction models for these patients, and lately, focus has shifted to artificial intelligence-based models, with employment of variable supervised and unsupervised techniques.

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  • This study compares two surgical methods, Hartmann's procedure (HP) and resection with primary anastomosis (RPA), for treating acute left-sided colonic emergencies among 1215 patients from 204 centers globally.
  • Results showed that while HP was the more common treatment (57.3%), RPA was favored for younger patients with fewer health issues and those needing surgery sooner.
  • The study concluded that although HP is still widely used, RPA might be the better option, emphasizing the importance of patient characteristics and surgeon experience in determining treatment choice.
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  • The study focuses on developing a predictive model called SEAL to assess the risk of serious postoperative complications after emergency laparotomy (EL), aiming to improve patient management.
  • Researchers analyzed data from 633 patients and identified six key predictors for complications, demonstrating that SEAL has strong accuracy and calibration compared to the existing ACS-NSQIP model.
  • The SEAL model is seen as a valuable tool for personalized risk assessment, with suggestions for further testing in diverse environments to validate its effectiveness.
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Risk prediction and stratification of short-term and long-term postoperative outcomes are growing in importance and scope of application in everyday clinical practice [...

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Background: Accurate preoperative risk assessment in emergency laparotomy (EL) is valuable for informed decision making and rational use of resources. Available risk prediction tools have not been validated adequately across diverse health care settings. Herein, we report a comparative external validation of four widely cited prognostic models.

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Preoperative risk stratification in the elderly surgical patient is an essential part of contemporary perioperative care and can be done with the use of the American College of Surgeons Surgical Risk Calculator (ACS-SRC). However, data on the generalizability of the ACS-SRC in the elderly is scarce. In this study, we report an external validation of the ACS-RC in a geriatric cohort.

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  • - The study investigates the outcomes of emergency laparotomy (EL) in Greece, comparing results with the National Emergency Laparotomy Audit (NELA) to understand patient outcomes and mortality rates.
  • - Conducted from 01.2019 to 05.2020, the study included 633 patients in 11 Greek hospitals, revealing a 30-day post-operative mortality rate of 16.3% and identifying risk factors such as age, ASA class, and pre-existing health conditions.
  • - Results show that while patient demographics were similar between Greece and the UK, the Greek cohort had significantly higher mortality rates and lower ICU utilization, indicating a potential quality of care issue that may contribute to the worse outcomes.
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Polymyalgia Rheumatica (PMR) is a syndrome characterized by chronic pain and/or stiffness in the neck, shoulders or upper arms and hips. It affects adult patients usually over 50 years old and is treated with low-dose oral corticosteroids. In this case, a 68-year-old female with a history of PMR, diagnosed by a specialist sporadically seen in the past, presented to a primary care physician due to herpes zoster (HZ) infection.

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In the modern era of prehabilitation, identifying malnourished surgical patients and optimising their nutritional status is crucial [...

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Background: In the past decades, the perioperative management of patients undergoing pancreaticoduodenectomy (PD) has undergone major changes worldwide. This review aimed to systematically determine the burden of complications of PD performed in the last 10 years.

Data Sources: A systematic review was conducted in PubMed for randomized controlled trials and observational studies reporting postoperative complications in at least 100 PDs from January 2010 to April 2020.

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The optimal malnutrition screening tool in geriatric surgery has yet to be determined. Herein, we compare two main tools in older patients undergoing general surgery operations. Older patients (>65 years old) who underwent general surgery operations between 2012 and 2017 in a tertiary centre were included.

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  • Using ultrasonography as a first-line imaging tool for suspected costal cartilage fractures can be really important.
  • In this case report, a patient with a possible fracture from repeated vomiting had a non-displaced and incomplete cartilage fracture that didn't show up on a CT scan.
  • However, ultrasound showed soft tissue swelling and bruising around the cartilage, helping to identify a subtle bone injury that might have been missed otherwise.
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This study aimed to assess satisfaction and report on perceptions of General Practice (GP) residents during residency in Greece, through an online questionnaire at a national level. A mixed type method study was shaped. Both quantitative analysis and a quasiqualitative approach were used, while information from an open-ended question was processed.

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Adenomyomatosis of the gallbladder is defined as hypertrophy of the gallbladder mucosal epithelium that invaginates into a thickened muscularis propria, leading to the formation of intramural diverticula. It is typically considered a benign condition most commonly affecting adults and, rarely, children. In this case report, we present a case of gallbladder adenomyomatosis in a 3-month-old infant.

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