Publications by authors named "Stamatia Papagiannarou"
Correction to: Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients.
Juliana de Castilhos Eli Zamir Theresa Hippchen Roman Rohrbach Sabine Schmidt Stamatia M Papagiannarou
Clin Infect Dis
August 2022
Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients.
Juliana de Castilhos Eli Zamir Theresa Hippchen Roman Rohrbach Sabine Schmidt Stamatia M Papagiannarou
Clin Infect Dis
August 2022
Article Synopsis
- The oropharyngeal microbiome may influence the immune response during respiratory virus infections, including COVID-19, with evidence suggesting that SARS-CoV-2 infection alters microbiome profiles.
- A multicenter study evaluated the microbiomes of healthy individuals and COVID-19 patients at various infection severities, finding that moderate to severe cases exhibited significant microbial imbalances compared to mild cases.
- Machine learning models identified specific microbial signatures, particularly involving Neisseria and Haemophilus species, that could predict mortality in COVID-19 patients, indicating that while the infection impacts microbiome, other factors also play a role.
Diabetic nephropathy correlates more closely to defective mitochondria and increased oxidative stress in the kidney than to hyperglycemia. A key driving factor of diabetic nephropathy is angiotensin II acting via the G-protein-coupled cell membrane type 1 receptor. The present study aimed to investigate the role of the angiotensin II type 2 receptor (AT2R) at the early stages of diabetic nephropathy.
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