Value-based decision-making in regular alcohol consumers following experimental manipulation of alcohol value.

Background: Devaluation of alcohol leads to reductions in alcohol choice and consumption; however, the cognitive mechanisms that underpin this relationship are not well-understood. In this study we applied a computational model of value-based decision-making (VBDM) to decisions made about alcohol and alcohol-unrelated cues following experimental manipulation of alcohol value.

Method: Using a pre-registered within-subject design, thirty-six regular alcohol consumers (≥14 UK units per week) completed a two-alternative forced choice task where they chose between two alcohol images (in one block) or two soft drink images (in a different block) after watching videos that emphasised the positive (alcohol value), and separately, the negative (alcohol devalue) consequences of alcohol.

The correlation between conspiracy mentality and vaccine intentions is moderated by social events: Evidence from longitudinal data during COVID-19 pandemic in the UK.

Social events may provide important cues that influence the sense of reality, including the perception that conspiracy theories are plausible. Using longitudinal panel data collected in the UK from March 2020 to December 2021, this study aims to identify whether social events influenced the strength of the association between conspiracy mentality and vaccine intentions during the COVID-19 pandemic. Consistent with previous research, the conspiracy mentality was a significant predictor of vaccine intentions across three-time points, but also that conspiracy mentality measured in March 2020 predicted that participants were more hesitant to the vaccines in December 2020.

Exploring the multiverse of analysis options for the alcohol Stroop.

The alcohol Stroop is a widely used task in addiction science to measure the theoretical concept of attentional bias (a selective attention to alcohol-related cues in the environment), which is thought to be associated with clinical outcomes (craving and consumption). However, recent research suggests findings from this task can be equivocal. This may be because the task has many different potential analysis pipelines, which increase researcher degrees of freedom when analysing data and reporting results.

The three-dimensional community structure of attention-deficit hyperactivity disorder (ADHD) traits captured by the Adult ADHD Self-Report Scale: An exploratory graph analysis.

Objective: To employ a novel analytic method-namely, exploratory graph analysis (EGA)-to subclinical attention-deficit hyperactivity disorder (ADHD) trait scores in order to reveal their dimensional structure, as well as compare EGA's performance with traditional factor-analytic techniques in doing so.

Method: 1149 respondents from a survey panel completed the ASRS, a common ADHD scale made up of 18 distinct trait measures. EGA and factor analysis were applied to identify traits which associate with each other.

Where next for partial randomisation of research funding? The feasibility of RCTs and alternatives.

We outline essential considerations for any study of partial randomisation of research funding, and consider scenarios in which randomised controlled trials (RCTs) would be feasible and appropriate. We highlight the interdependence of target outcomes, sample availability and statistical power for determining the cost and feasibility of a trial. For many choices of target outcome, RCTs may be less practical and more expensive than they at first appear (in large part due to issues pertaining to sample size and statistical power).

The genome and diet of a 35,000-year-old specimen from the Paleolithic painted cave, Chauvet-Pont d'Arc, France.

The Chauvet-Pont-d'Arc Cave (Ardèche, France) contains some of the oldest Paleolithic paintings recorded to date, as well as thousands of bones of the extinct cave bear, and some remains and footprints of other animals. As part of the interdisciplinary research project devoted to this reference cave site, we analyzed a coprolite collected within the deep cave. AMS radiocarbon dating of bone fragments from the coprolite yielded an age of 30,450 ± 550 RC yr.

Recovery From Nicotine Addiction: A Diffusion Model Decomposition of Value-Based Decision-Making in Current Smokers and Ex-smokers.

Introduction: A considerable number of people successfully give up tobacco smoking. In nicotine-dependent individuals, tobacco choice is determined by greater expected drug value; however, less is known about the underlying mechanisms through which people quit smoking.

Aims And Methods: This study aimed to explore whether computational parameters of value-based decision-making (VBDM) characterize recovery from nicotine addiction.

Using dialogues to increase positive attitudes towards COVID-19 vaccines in a vaccine-hesitant UK population.

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Mind the gap: Distributed practice enhances performance in a MOBA game.

Understanding how humans master complex skills has the potential for wide-reaching societal benefit. Research has shown that one important aspect of effective skill learning is the temporal distribution of practice episodes (i.e.

Behavioral economic and value-based decision-making constructs that discriminate current heavy drinkers versus people who reduced their drinking without treatment.

Objective: A substantial number of people reduce their consumption of alcohol in the absence of formal treatment; however, less is known about the mechanisms of change. The aim of this study is to explore whether constructs derived from behavioral economics and computational decision-modeling characterize the moderation of alcohol consumption that many heavy drinkers experience without treatment.

Method: Between-subject, preregistered design.

Utilization of Improvement Methodologies by Healthcare Quality Professionals During the COVID-19 Pandemic.

Introduction: This study describes the work of healthcare quality professionals during the COVID-19 pandemic, highlighting the successes and challenges they faced when applying their expertise in performance and process improvement (PPI) to help manage the crisis.

Methods: The researchers performed a descriptive analysis of anonymous survey data collected from members of the National Association for Healthcare Quality professional community who were asked about their improvement work during the pandemic response.

Results: Most survey respondents used improvement methods to a great or moderate extent to measure what was happening (83%), rapidly review processes and practice (81%), and decide where to focus effort (81%).

Revisiting proboscidean phylogeny and evolution through total evidence and palaeogenetic analyses including ancient DNA.

The extinct Gomphotheriidae is the only proboscidean family that colonized South America. The phylogenetic position of the endemic taxa has been through several revisions using morphological comparisons. Morphological studies are enhanced by paleogenetic analyses, a powerful tool to resolve phylogenetic relationships; however, ancient DNA (aDNA) preservation decreases in warmer regions.

Magnitude-sensitivity: rethinking decision-making.

Magnitude-sensitivity refers to the result that performance in decision-making, across domains and organisms, is affected by the total value of the possible alternatives. This simple result offers a window into fundamental issues in decision-making and has led to a reconsideration of ecological decision-making, prominent computational models of decision-making, and optimal decision-making. Moreover, magnitude-sensitivity has inspired the design of new robotic systems that exploit natural solutions and apply optimal decision-making policies.

Why Competency Standardization Matters for Improvement: An Assessment of the Healthcare Quality Workforce.

Healthcare transformation requires a healthcare quality workforce with the requisite expertise to lead, oversee, and implement positive change within healthcare organizations. The National Association for Healthcare Quality (NAHQ) Competency Framework, which spans 29 competencies across 8 domains of healthcare quality, outlines the specific knowledge and skills needed to advance personal and organizational quality goals. This study describes 1,671 responses to the NAHQ Professional Assessment survey from a diverse group of healthcare quality professionals representative of NAHQ's professional community.

Online informational bariatric seminars: increasing access to bariatric surgery or widening a divide?

Background: Historically our institution has required prospective bariatric patients attend an in-person introductory seminar prior to their first clinic visit. Utilization of the internet has increased dramatically over the last 10 years and in 2016, we added an online seminar. With the emergence of COVID-19 and new rules regarding social distancing, we are currently relying exclusively on web-based orientation.

Fulminant Enteroviral Myocarditis in a Newborn Accompanying Maternal SARS-CoV-2 Infection.

We present a case of fulminant myocarditis in a preterm neonate born to a SARS-CoV-2-infected mother with COVID-19 disease. Despite complete separation after birth, cardiogenic decompensation initiated on day of life 7. Although the neonate tested negative for SARS-CoV-2, enterovirus viremia accompanied cardiac dysfunction, multiorgan failure, and neonatal death within 36 hours.

The relationship between sensory processing sensitivity and attention deficit hyperactivity disorder traits: A spectrum approach.

The aim of the present study was to examine the relationship between sensory processing sensitivity (SPS) and symptoms of Attention Deficit Hyperactivity Disorder (ADHD) in adults. The Highly Sensitive Person Scale (HSPS) scale and the Adult ADHD Self-Report Scale (ASRS) were administered to a non-clinical group of 274 participants recruited from a university volunteers list. We found a highly significant positive correlation between number of self-reported ADHD traits and sensory sensitivity.

The age of Clovis-13,050 to 12,750 cal yr B.P.

Thirty-two radiocarbon ages on bone, charcoal, and carbonized plant remains from 10 Clovis sites range from 11,110 ± 40 to 10,820 ± 10 C years before the present (yr B.P.).

Rapid range shifts and megafaunal extinctions associated with late Pleistocene climate change.

Large-scale changes in global climate at the end of the Pleistocene significantly impacted ecosystems across North America. However, the pace and scale of biotic turnover in response to both the Younger Dryas cold period and subsequent Holocene rapid warming have been challenging to assess because of the scarcity of well dated fossil and pollen records that covers this period. Here we present an ancient DNA record from Hall's Cave, Texas, that documents 100 vertebrate and 45 plant taxa from bulk fossils and sediment.

Evidence for the rationalisation phenomenon is exaggerated.

The evidence for rationalisation, which motivates the target article, is exaggerated. Experimental evidence shows that rationalisation effects are small rather than gross and, I argue, largely silent on the pervasiveness and persistence of the phenomenon. At least some examples taken to show rationalisation also have an interpretation compatible with deliberate, knowing reason-responsiveness on the part of participants.

Quantifying the benefits of using decision models with response time and accuracy data.

Response time and accuracy are fundamental measures of behavioral science, but discerning participants' underlying abilities can be masked by speed-accuracy trade-offs (SATOs). SATOs are often inadequately addressed in experiment analyses which focus on a single variable or which involve a suboptimal analytic correction. Models of decision-making, such as the drift diffusion model (DDM), provide a principled account of the decision-making process, allowing the recovery of SATO-unconfounded decision parameters from observed behavioral variables.

Slowed Luminance Reaction Times in Cervical Dystonia: Disordered Superior Colliculus Processing.

Background: Abnormal temporal discrimination in cervical dystonia is hypothesized to be attributable to disrupted processing in the superior colliculus. The fast, luminance-based, retinotectal pathway, projects to the superior colliculus; chromatic stimuli responses, by the retino-geniculo-calcarine pathway, are up to 30 ms longer.

Objectives: We sought to interrogate visual processing and reaction times in patients with cervical dystonia compared with healthy controls.

Cognitive control across adolescence: Dynamic adjustments and mind-wandering.

Models of cognitive development suggest that cognitive control, a complex construct that ensures goal-directedness even in the face of distractions, is still maturing across adolescence. In the present study, we investigated how the ability to dynamically adjust cognitive control develops in this period of life, as indexed by the magnitude of the congruency sequence effect (CSE) in conflict tasks, and how this ability might relate to lapses of attention (mind-wandering [MW]). To these ends, participants from four age groups (12-13, 14-15, 18-20 and 25-27 years old) completed confound-minimized variants of the flanker and Simon tasks, along with a Go/No-Go task with thought probes to assess their frequency of mind-wandering.

Recovery from addiction: Behavioral economics and value-based decision making.

Behavioral economics provides a general framework to explain the shift in behavioral allocation from substance use to substance-free activities that characterizes recovery from addiction, but it does not attempt to explain the internal processes that prompt those behavioral changes. In this article we outline a novel analysis of addiction recovery based on computational work on value-based decision making (VBDM), which can explain how people with addiction are able to overcome the reinforcement pathologies and decision-making vulnerabilities that characterize the disorder. The central tenet of this account is that shifts in molar reinforcer preferences over time from substance use to substance-free activities can be attributed to changes in evidence accumulation rates and response thresholds in the context of choices involving substance use and substance-free alternatives.