Abstinence based incentives plus parent training for adolescent alcohol and other substance misuse.

The purpose of this study was to conduct a randomized test of clinic- and home-based incentives plus parent training for adolescent problem alcohol use. Adolescents (N = 75) with alcohol misuse, with or without other substance misuse, were enrolled. All youth received individual Motivational Enhancement Therapy/Cognitive Behavior Therapy and weekly urine drug testing.

Acute effects of methylphenidate on impulsivity and attentional behavior among adolescents comorbid for ADHD and conduct disorder.

Adolescents with Attention Deficit Hyperactivity Disorder (ADHD) and Conduct Disorder (CD) experience deficits in neuropsychological measures of attention, inhibition, and reward processes. Methylphenidate treatment for ADHD and CD has acute effects on these processes. Some of these same aspects of performance are separately described in the Behavioral Model of Impulsivity, which uses a modified approach to measurement.

Early Adolescent Trajectories of Impulsiveness and Sensation Seeking in Children of Fathers with Histories of Alcohol and Other Substance Use Disorders.

Background: Problem substance use often begins in adolescence. This vulnerability likely stems, at least partially, from relatively rapid increases in sensation seeking occurring in early to mid-adolescence and more gradual improvements in impulse control occurring through later adolescence. Better understanding how these processes develop in high-risk youth may lead to enhanced substance use disorder treatment and prevention strategies.

Child Problems as a Moderator of Relations Between Maternal Impulsivity and Family Environment in a High-Risk Sample.

Objective: Previous studies have suggested that maternal characteristics are related to family environment; however, the relation between maternal impulsivity, in particular, and family environment is not well understood. As such, we examined direct relations between maternal impulsivity and family environment, as well as whether the relation between maternal impulsivity and family environment was moderated by child problems for sons and daughters. We hypothesized that child problems would moderate the association between maternal impulsivity and family environment.

Pubertal Maturation Compression and Behavioral Impulsivity among Boys at Increased Risk for Substance Use.

Objectives: While early onset of puberty among girls has been related to substance use involvement and other adverse outcomes, less research has examined pubertal development and outcomes in boys. Further, research on puberty has not been conducted in the context of other risk factors for substance use involvement such as impulsivity. To address these gaps, this study characterized boys' pubertal development from preadolescence to mid-adolescence and related it to substance use risk and behavioral impulsivity.

Altered developmental trajectories for impulsivity and sensation seeking among adolescent substance users.

A number of studies have associated impulsivity and sensation seeking with level of substance use and risk for developing a substance use disorder. These relationships may be particularly apparent during adolescence, when developmental changes in impulsivity and sensation seeking occur at the same time as increased opportunities for substance use. To examine this, the current study measured impulsivity and sensation seeking from pre-adolescence to mid-adolescence in a sample of youth, the majority of whom were identified as being at risk for developing a substance use disorder based on their family history of substance use disorders.

Family Functioning as a Mediator of Relations between Family History of Substance Use Disorder and Impulsivity.

Unlabelled: Impulsivity is strongly related to the development of adolescent substance use. Therefore, understanding factors that influence impulsive characteristics is important for the development of prevention and intervention programs. Intervention and prevention programs focused on factors that influence impulsive characteristics are especially important for those at particularly high risk for the expression of impulsivity - those with a family history of substance use disorder.

Clinical and Social/Environmental Characteristics in a Community Sample of Children With and Without Family Histories of Substance Use Disorder in the San Antonio Area: A Descriptive Study.

This is a descriptive study of the recruitment and clinical/environmental characteristics of a child cohort (ages 10-12) established to test transmission of impulsivity in children with (FH+; n = 305) and without (FH-; n = 81) family history of substance use disorder. Among this cohort FH children had more emotional and behavioral symptoms, worse family relationships, and more deviant peers compared to FH children. This cohort of children was established prior to the initiation of regular substance use and significant clinical problems, which will allow the opportunity to examine reciprocal relations between development of impulse control and substance use development.

Feasibility of a computer-assisted alcohol screening, brief intervention and referral to treatment program for DWI offenders.

Background: Alcohol use patterns that are hazardous for one's health is prevalent among DWI (driving while intoxicated) offenders and is a key predictor of recidivism. The aim of this program evaluation was to determine the feasibility and usability of implementing a computer-assisted screening, brief intervention and referral to treatment (SBIRT) program for DWI offenders to enable the identification of those in need of treatment services soon after arrest. Our treatment program consisted of a web-based, self-guided screening tool for assessing alcohol use patterns and generating a personalized feedback report that is then used to deliver a brief motivational intervention and if needed, a referral to treatment.

Behavioral Impulsivity and Risk-Taking Trajectories Across Early Adolescence in Youths With and Without Family Histories of Alcohol and Other Drug Use Disorders.

Background: Youths with family histories of alcohol and other drug use disorders (FH+) are at increased susceptibility for developing substance use disorders relative to those without such histories (FH-). This vulnerability may be related to impaired adolescent development of impulse control and elevated risk-taking. However, no previous studies have prospectively examined impulse control and risk-taking in FH+ youth across adolescence.

Clinic- and home-based contingency management plus parent training for adolescent cannabis use disorders.

Objective: The aim of this study was to conduct a randomized test comparing 2 multicomponent, contingency management interventions, 1 with and 1 without a full parent training curriculum, and an individual treatment for adolescent cannabis use disorders.

Method: A total of 153 adolescents who met DSM-IV criteria for cannabis abuse or dependence were randomized to motivational enhancement therapy/cognitive-behavioral therapy (MET/CBT), MET/CBT+abstinence-based contingency management (CM), or MET/CBT+CM+Parent Training (PT).

Results: Overall, during treatment, abstinence was greater for youth receiving clinic- and home-based CM without PT compared to those who received individual MET/CBT.

Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation.

Individuals with a family history of substance use disorders (Family History Positive) are more likely to have early-onset substance use (i.e., prior to age 15), which may contribute to their higher rates of substance use disorders.

Treatment Needs of Driving While Intoxicated Offenders: The Need for a Multimodal Approach to Treatment.

Objective: This study aimed to characterize and compare the treatment needs of adults with driving while intoxicated (DWI) offenders recruited from a correctional residential treatment facility and the community to provide recommendations for treatment development.

Method: A total of 119 adults (59 residential, 60 community) with at least one DWI offense were administered clinical diagnostic interviews to assess substance use disorders and completed a battery of questionnaires assessing demographic characteristics, legal history, psychiatric diagnoses, medical diagnoses, and health care utilization.

Results: Almost all (96.

Childhood stress exposure among preadolescents with and without family histories of substance use disorders.

Having a family history of substance use disorders (FH+) increases risk for developing a substance use disorder. This risk may be at least partially mediated by increased exposure to childhood stressors among FH+ individuals. However, measures typically used to assess exposure to stressors are narrow in scope and vary across studies.

Delay discounting differentiates pre-adolescents at high and low risk for substance use disorders based on family history.

Background: Youth with family histories of substance use disorders (FH+) are at increased risk for developing substance use disorders relative to those without such histories (FH-). FH+ individuals show deficits in impulse control that parallel those in individuals with substance use disorders. Elucidating how specific components of impulse control are affected in FH+ pre-adolescents would advance our understanding of how deficits in impulse control relate to risk of substance use disorders.

Neuroeconomics and adolescent substance abuse: individual differences in neural networks and delay discounting.

Objective: Many adolescents with substance use problems show poor response to evidence-based treatments. Treatment outcome has been associated with individual differences in impulsive decision making as reflected by delay discounting (DD) rates (preference for immediate rewards). Adolescents with higher rates of DD were expected to show greater neural activation in brain regions mediating impulsive/habitual behavioral choices and less activation in regions mediating reflective/executive behavioral choices.

A multicomponent motivational intervention to improve adherence among adolescents with poorly controlled type 1 diabetes: a pilot study.

Objective: To adapt and pilot test a multicomponent motivational intervention that includes family-based contingency management (CM) for adolescents with poorly controlled type 1 diabetes.

Methods: A total of 17 adolescents, age 12-17 years (M = 14.8, SD = 1.

Predictors of Therapist Adherence and Emotional Bond in Multisystemic Therapy: Testing Ethnicity as a Moderator.

This study examined the interaction between problem severity and race\ethnicity as a predictor of therapist adherence and family-therapist emotional bond. Data for this study came from a longitudinal evaluation of Multisystemic Therapy (MST) provided by licensed MST provider organizations in community settings. Outcome variables included mid-treatment levels of caregiver report of therapist adherence, changes in caregiver report of therapist adherence over the course of treatment, and overall levels of caregiver-therapist and youth-therapist emotional bond.

Biosocial processes predicting multisystemic therapy treatment response.

This study examined biological (testosterone) and social (deviant peer affiliation) factors early in treatment as predictors of treatment outcome among adolescent boys receiving Multisystemic Therapy (MST) in community settings. Outcome variables included changes in youth aggression and delinquency as reported by the primary caregiver. Testosterone and deviant peer affiliation were assessed at treatment onset; and outcome variables (aggression and delinquency) were assessed at treatment onset, mid-treatment and end-of-treatment.

The impact of disruptive behavior disorder on substance use treatment outcome in adolescents.

The current study examined the impact of disruptive behavior disorder (DBD) on substance use outcomes in an adolescent sample. Sixty-eight adolescents and their caregivers were randomized to one of two fourteen-week, outpatient treatments: Motivational Enhancement Therapy/Cognitive Behavior Therapy (MET/CBT)+Parent Management Training+Contingency Management (CM; experimental) and MET/CBT+Parent Drug Education (attention control). This study assessed abstinence, substance use, externalizing behavior, and parenting outcomes over five assessment periods for youth with DBD (DBD(+)) and without DBD (DBD(-)).

Perinatal factors, parenting behavior, and reactive aggression: does cortisol reactivity mediate this developmental risk process?

Little is known about the mechanisms of action that link perinatal risk and the development of aggressive behavior. The aim of this study was to examine whether perinatal risk and parenting interacted to specifically predict reactive aggression, as opposed to general aggressive behavior, and to examine cortisol reactivity as a mediator of this developmental risk process. In a community sample of 99 elementary school-aged children, prenatal risk was measured by a count of minor physical anomalies (MPAs), reactive aggression was measured by laboratory observations of aggression in response to provocation, and general aggression was measured by parent report.

Delay discounting predicts adolescent substance abuse treatment outcome.

The purpose of the current study was to identify predictors of delay discounting among adolescents receiving treatment for marijuana abuse or dependence, and to test delay discounting as a predictor of treatment outcome. Participants for this study were 165 adolescents (88% male) between the ages of 12 and 18 (mean age = 15.8 years; standard deviation = 1.