Pharmacokinetics of voriconazole after oral administration of single and multiple doses in African grey parrots (Psittacus erithacus timneh).

Objective: To determine the pharmacokinetics and safety of orally administered voriconazole in African grey parrots.

Animals: 20 clinically normal Timneh African grey parrots (Psittacus erithacus timneh).

Procedures: In single-dose trials, 12 parrots were each administered 6, 12, and 18 mg of voriconazole/kg orally and plasma concentrations of voriconazole were determined via high-pressure liquid chromatography.