Performance of IOTA Simple Rules Risks, ADNEX Model, Subjective Assessment Compared to CA125 and HE4 with ROMA Algorithm in Discriminating between Benign, Borderline and Stage I Malignant Adnexal Lesions.

Background: Borderline ovarian tumors (BOTs) and early clinical stage malignant adnexal masses can make sonographic diagnosis challenging, while the clinical utility of tumor markers, e.g., CA125 and HE4, or the ROMA algorithm, remains controversial in such cases.

Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems.

Background: Abnormal uterine bleeding (AUB) represents a common diagnostic challenge, as it might be related to both benign and malignant conditions. Endometrial cancer may not be detected with blind uterine cavity sampling by dilatation and curettage or suction devices. Several scoring systems using different ultrasound image characteristics were recently proposed to estimate the risk of endometrial cancer (EC) in women with AUB.

Sonographic Assessment of Complex Ultrasound Morphology Adnexal Tumors in Pregnant Women with the Use of IOTA Simple Rules Risk and ADNEX Scoring Systems.

Background: To evaluate the accuracy of subjective assessment (SA), the International Ovarian Tumor Analysis (IOTA) group Simple Rules Risk (SRR) and the Assessment of Different NEoplasias in the adneXa (ADNEX) model for the preoperative differentiation of adnexal masses in pregnant women.

Methods: The study population comprised 36 pregnant women (median age: 28.5 years old, range: 20-42 years old) with a mean gestation age of 13.

Electronic Health Records and Pulmonary Function Data: Developing an Interoperability Roadmap. An Official American Thoracic Society Workshop Report.

A workshop "Electronic Health Records and Pulmonary Function Data: Developing an Interoperability Roadmap" was held at the American Thoracic Society 2019 International Conference. "Interoperability" is defined as is the ability of different information-technology systems and software applications to directly communicate, exchange data, and use the information that has been exchanged. At present, pulmonary function test (PFT) equipment is not required to be interoperable with other clinical data systems, including electronic health records (EHRs).

Tumor budding index and microvessel density assessment in patients with endometrial cancer: A pilot study.

The present study aimed to analyze the association between tumor budding index (TBI) and microvessel density (MVD) and selected clinicopathological features in female patients with endometrial cancer (EC). The present study included 137 patients, of whom 117 had endometrial endometrioid cancer and 3 had non-endometrioid EC (NEEC). Additionally, 8 cases of simple endometrial hyperplasia and 9 cases of atypical endometrial hyperplasia were included in the present study.

[Breasts self examination - everything we want you to know about it - survey study].

Objective: Introduction: Breasts self examination is first line prevention in case of breast cancer. It is cheap, it is easy and it can save your life. That is why it is so important that every woman and even man know how to do it.

[testicles self examination - knowledge and abilities - survey study].

Objective: Introduction: Testicle cancer is a common malignant cancer among young men (20 to 44 years). In 90% of cases we can feel nodule or change of consistency, which means during testicles self examination we can quickly discover cancer. The aim: To estimate the level of knowledge about testicles self examination among men and also medical stuff and students.

[Public knowledge of the infertility and legal aspects of infertility treatment in Poland].

Objective: Introduction: The awareness of infertility is limited in Polish society despite the fact that this problem affects around one million couples in our country. Some of them decide to undergo specialistic treatment. Issues pertaining techniques of contributed reproduction are strictly regulated by Polish law.

Prognostic significance of TEM7 and nestin expression in women with advanced high grade serous ovarian cancer.

Objectives: Tumor endothelial marker 7 (TEM7) and nestin have been proposed to be new candidates for neoangiogenesis assessment. Nestin is also cancer stem cells marker in various malignant tumors.

Aims: To investigate the expression of TEM7, nestin and nestin-related microvessel density (MVD) in high-grade serous ovarian cancer samples and to study their correlation with overall survival (OS) and disease-free survival (DFS) times.

The use of sonographic subjective tumor assessment, IOTA logistic regression model 1, IOTA Simple Rules and GI-RADS system in the preoperative prediction of malignancy in women with adnexal masses.

Background: Sonography based methods with various tumor markers are currently used to discriminate the type of adnexal masses.

Objective: To compare the predictive value of selected sonography-based models along with subjective assessment in ovarian cancer prediction.

Material And Methods: We analyzed data of 271 women operated because of adnexal masses.

Diagnostic hysteroscopy and the risk of malignant cells intraabdominal spread in women with endometrial cancer.

Although hysteroscopy is currently the undisputed gold standard for the examination of the uterine cavity in women with suspected endometrial cancer, it remains controversial as a procedure that can enhance metastasis spread. Endometrial cancer cells may shed during hysteroscopy and be passively transported with fluid flow into the peritoneal cavity. The paper presents the review of current knowledge regarding the risk of neoplasm metastases in women who had diagnostic hysteroscopy and the conditions that have to be met for the procedure to be safe.

Mig-7 expression and vasculogenic mimicry in malignant ovarian tumors.

Objectives: To investigate the possible association of vasculogenic mimicry (VM), VE-cadherin and MIG-7 expression with clinicopathological features of women with malignant ovarian masses.

Material And Methods: VM was studied with the PAS reaction and VE-cadherin was assessed with immunohistochemistry in 108 women with malignant ovarian tumors. Additionally, quantitative expression of MIG-7 mRNA was performed in 52 ovarian cancers with qRT-PCR.

Proliferation and maturation of intratumoral blood vessels in women with malignant ovarian tumors assessed with cancer stem cells marker nestin and platelet derived growth factor PDGF-B.

Objectives: Platelet-derived growth factor B (PDGF-B) and nestin have been suggested to be useful in the assessment of neoangiogenesis in malignant ovarian masses. We aimed to investigate a possible association of these markers with newly formed microcapillaries and perivascular cells in ovarian tumors.

Material And Methods: Microvessel density (MVD) and pericytes were studied in 82 women with ovarian neoplasms, including 7 benign cysts, 7 borderline masses, 64 epithelial ovarian cancers and 4 other malignant ovarian tumors.

Extracellular matrix proteins in healthy and retained placentas, comparing hemochorial and synepitheliochorial placentas.

The placenta expresses structural and biologically active proteins. Their synthesis is mainly regulated by genomic or nongenomic signals and modulated by hormones. These protein profiles are altered during different stages of pregnancy.

[What do we konw about the Zika virus?].

Zika virus (HIV) was first identified in 1947 and upto 2007 the infections in humans have been reported sporadically. Currently, the World Health Organization warns that the rapid spread of the virus Zika in both Americas and an increase in the number of children born with microcephaly in these regions begins to be a serious epidemiological problem. Known ways of spreading this RNA virus of the Flaviviridae family is: with blood, sexual, vertical and even breast feeding.

[Skręt sieci większej jako przyczyna dolegliwości bólowych miednicy mniejszej u pacjentki po cięciu cesarskim - trudności diagnostyczne].

Spontaneous torsion of the greater omentum is a rare cause of the acute abdomen or pain complaints of the pelvis minor. It can imitate an severe inflammatory conditions rolling in the peritoneal cavity like e.g.

[What do we konw about the Zika virus?].

Zika virus (HIV) was first identified in 1947 and upto 2007 the infections in humans have been reported sporadically. Currently, the World Health Organization warns that the rapid spread of the virus Zika in both Americas and an increase in the number of children born with microcephaly in these regions begins to be a serious epidemiological problem. Known ways of spreading this RNA virus of the Flaviviridae family is: with blood, sexual, vertical and even breast feeding.

[Clitoromegaly--treatment with the harmonic knife (case description)].

Clitoromegaly, state when clitoris is non-physiologically large, most frequently occurs among patients with endocrine disorders (adrenal-genital syndrome, hormonally active tumors producing androgens, the use of anabolic steroids) or genetic. Less often the clitoromegaly is idiopathic of unknown etiology. There are no fixed standards for the size of organ, but it is assumed that not being in erect clitoris due to sexual arousal has a diameter of no more than 1/2 cm.

[Assessment of the angle between puborectal muscles in women with and without stress urinary incontinence in three-dimensional sonograph].

Unlabelled: Contemporary care of the woman, especially in the postmenopausal period is based not only on gynaecological periodic inspections, but also on the routine evaluation of the pelvis minorwith the ultrasound examination. Based on this examination we can manytimes initially diversify causes of wrong manifestations, so like, e.g.

[Ultrasonography in the diagnostics of reasons for the urinary incontinence at the postmenopausal woman. Part II--Three-dimensional ultrasonography].

In this article a new abilities of lower urinary tract diagnosis in three-dimensional sonography were shown. The examination's components, which allow us to estimate anatomical changes in patients with urinary incontinence were described.

[The role of gut microbiota in the pathogenesis of obesity and diabetes].

The rapidly increasing number of people with obesity and type 2 diabetes is one of the most serious problems of the contemporary world. Until recently, it was thought that the main cause of this phenomenon is the change of lifestyle and dietary habits. According to recent reports, the gut microbiota may also play an important role in the "epidemic" of obesity and diabetes.

[Sonographic evaluation of the levator ani muscle in women with stress urinary incontinence].

Unlabelled: Three-dimensional sonography has been used for about 15 years, not only to examine the female genital organs, but also the lower urinary tract and pelvic floor. Three-dimensional sonography offers more information than traditional two-dimensional sonography allowing for a dynamic representation of the examined structures and observation at any angle necessary. Translabial sonography is the best way of a sonographic examination of the lower urinary tract, because it does not affect the mutual relationship of any parts in the lower pelvic area, contrary to the transrectal or transvaginal probes.

[Urgent urinary incontinence--preliminary diagnostics and pharmacological treatment].

In this paper authors describe classification, preliminary diagnosis of urinary incontinence. They also show ways of pharmacological therapy and kinds of available medicines, which are administer in treatment of women with urinary incontinence symptoms of neurologic descent and overactive bladder.

The influence of age and gender on antioxidant enzyme activities in humans and laboratory animals.

Antioxidative/oxidative balance is one of the important factors for homeostasis. Antioxidative systems which protect from peroxidative damage are supposed to be under the influence of steroid hormones. The implications of this influence are age and gender as well as tissue dependent alterations in antioxidative enzyme activities.

[Ultrasonography in the diagnostics of reasons for the urinary incontinence at the postmenopausal woman. Part I--Two-dimensional ultrasonography].

This article presents suitability of two-dimensional sonography in lower urinary tract diagnostics. Examination components, allowing for a detailed evaluation of anatomical changes in patients with urinary incontinence, were described.