Publications by authors named "Stabilini C"

Article Synopsis
  • Clinical guidelines are evidence-based recommendations created by experts to help healthcare providers and patients make informed decisions about health conditions, ultimately improving healthcare quality and tailored care.
  • The European Hernia Society (EHS) guidelines specifically assist surgeons in managing abdominal wall defects with reliable answers to their clinical questions, traditionally developed through consensus among key opinion leaders.
  • The GRADE method enhances the quality of these guidelines by providing a structured approach to evaluating evidence and making recommendations, addressing challenges in guideline production and advocating for dedicated research groups to improve adherence to this methodology.
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Purpose: To evaluate the incidence of incisional hernia in patients undergoing direct access to the abdominal cavity in urological surgery.

Methods: We conducted a systematic review in Pubmed, Embase, and Cochrane Central from 1980 to the present according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. Eighty-four studies were selected for inclusion in this analysis, and meta-analysis and meta-regression were performed.

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Introduction: Incisional hernia (IH) is a prevalent and potentially dangerous complication of abdominal surgery, especially in high-risk groups. Mesh reinforcement of the abdominal wall has been studied as a potential intervention to prevent IHs. Randomised controlled trials (RCTs) have demonstrated that prophylactic mesh reinforcement after abdominal surgery, in general, is effective and safe.

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Article Synopsis
  • The study aimed to evaluate how effective prophylactic mesh is for preventing parastomal hernias in end colostomy patients, ultimately contributing to European clinical guidelines.* -
  • The meta-analysis included 12 randomized trials, showing that while quality of life (QoL) was unaffected by the use of mesh, it significantly reduced the incidence of parastomal hernias (risk reduction OR = 0.33).* -
  • No significant differences were found in surgery requirements or severe complications associated with mesh use, suggesting that while the mesh helps reduce hernia rates, it doesn’t impact QoL or lead to more serious surgical issues.*
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Article Synopsis
  • A new guideline has been developed for preventing parastomal hernias, prompted by evidence supporting the use of prophylactic mesh and advancements in guideline methods.
  • An interdisciplinary panel, including surgeons, nurses, and patients, employed a systematic review and meta-analysis to create trustworthy recommendations based on GRADE standards.
  • The guideline recommends using prophylactic mesh for patients with end colostomies, particularly those at high risk, while acknowledging moderate evidence certainty for parastomal hernia prevention and identifying areas for future research.
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Article Synopsis
  • The study investigates the risks associated with performing simultaneous stoma reversal and incisional hernia repair compared to stoma reversal alone.
  • It analyzed data from 504 patients and found that combined surgery led to higher rates of surgical complications but no significant differences in mortality, hospital stays, or readmission rates.
  • The conclusion recommends considering a stepwise approach to surgeries to reduce the risk of complications, as synchronous procedures may elevate the likelihood of adverse outcomes.
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Article Synopsis
  • - Groin hernia repair is a highly common surgery, with over 20 million procedures done annually, prompting the need for updated management guidelines since the last ones were published in 2018.
  • - An expert group of 30 international surgeons reviewed new research until April 2022, resulting in updated guidelines with 39 new statements and 32 recommendations, including 16 strong ones.
  • - The updated guidelines aim to provide the latest evidence for better groin hernia management practices, with a commitment to adapt future guidelines as new methodologies emerge.
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Minimally invasive abdominal wall surgery is growing worldwide, with a constant and fast improvement of surgical techniques and surgeons' confidence in treating both primary and incisional hernias (IH). The Italian Society of Endoscopic Surgery and new technologies (SICE) and the ISHAWS (Italian Society of Hernia and Abdominal Wall Surgery) worked together to investigate state of the art in IH treatment in elective and emergency settings in Italy. An online open survey was designed, and Italian surgeons interested in abdominal wall surgery were invited to fill out a 20-point questionnaire on IH surgical procedures performed in their departments.

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Robot assisted laparoscopic abdominal wall surgery (RAWS) has seen a rapid adoption in recent years. The safe introduction of the robot platform in the treatment of abdominal wall hernias is important to safeguard the patient from harm during the learning curve. The scope of this paper is to describe the current European training curriculum in RAWS.

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Background: Incisional hernia is a frequent complication of abdominal wall incision. Surgical technique is an important risk factor for the development of incisional hernia. The aim of these updated guidelines was to provide recommendations to decrease the incidence of incisional hernia.

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Background: Ventral hernia repair is one of the most commonly performed surgical procedures worldwide. To reduce the risk of complications, pre- and intra-operative strategies have received increasing focus in recent years. To assess possible preventive surgical strategies, this European Hernia Society endorsed project was launched.

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Parastomal hernia presents frequently after construction of a permanent end colostomy. Previous guidelines recommend using a prophylactic mesh for hernia prevention. Randomized controlled trials (RCTs) published hereafter demonstrate conflicting outcomes.

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Background: Ventral hernia repair is one of the most commonly performed surgical procedures worldwide. To reduce the risk of complications, patient prehabilitation has received increasing focus in recent years. To assess prehabilitation measures, this European Hernia Society endorsed project was launched.

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Introduction: Total thyroidectomy (TT) is one of the most common procedures among general and endocrine surgeons worldwide. The conventional approach by neck incision is still the most frequently used, despite the growth of mini-invasive approaches. Controversies exist about the optimal learning curve for resident surgeons approaching this procedure.

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Purpose: To assess the incidence of incisional hernia (IH) across various type of incisions in colorectal surgery (CS) creating a map of evidence to define research trends, gaps and areas of future interest.

Methods: Systematic review of PubMed and Scopus from 2010 onwards. Studies included both open (OS) and laparoscopic (LS).

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Article Synopsis
  • Hernias are a common issue leading to surgery, but patients often have limited involvement in decision-making about their treatment.
  • Researchers aimed to understand patient perspectives on hernia management to improve future healthcare services and outcomes.
  • The study collected responses from 397 patients, highlighting the importance of having knowledgeable specialists, the desire for information on surgery impacts (like sexual function), and the need for better involvement in their care, especially regarding complications post-surgery.
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Purpose: To compare early postoperative outcomes after transversus abdominis release (TAR) for ventral hernia repair with open (oTAR) and robotic (rTAR) approach.

Methods: A systematic search of PubMed/MEDLINE, EMBASE, SCOPUS and Web of Science databases was conducted to identify comparative studies until October 2020. A meta-analysis of postoperative short-term outcomes was performed including complications rate, operative time, length of stay, surgical site infection (SSI), surgical site occurrence (SSO), SSO requiring intervention (SSOPI), systemic complications, readmission, and reoperation rates as measure outcomes.

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Introduction: Preoperative assessment of deep endometriotic (DE) nodules is necessary to inform patients about the possible treatments and provide informed consent in case of surgery. This study aims to investigate the diagnostic performance of rectal water-contrast transvaginal ultrasonography (RWC-TVS) and sonovaginography (SVG) in women with suspicion of posterior DE.

Material And Methods: This prospective comparative study (NCT04296760) enrolled women with clinical suspicion of DE at our institution (Piazza della Vittoria 14 SRL, Genoa, Italy).

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Background And Objectives: Colorectal cancer is still one of the leading causes of cancer-related deaths worldwide and specific tools to improve disease assessment and treatment response are advocated. The aim of this study was to analyze miRNAs expression in metastatic and non-metastatic colorectal cancer, in order to identify reliable biomarkers suitable for prognosis, treatment and patient's monitoring.

Material And Methods: Among 25 patients (mean age 71 ± 12 years; Female/Male: 12/13) submitted to laparoscopic colorectal resection between August 2017 and February 2019, miRNAs were extracted from fresh frozen tissues of solid tumors.

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Background: A currently unsolved problem of open inguinal hernia repair (IHR) is chronic postoperative inguinal pain (CPIP), which affects 10-12% of patients after IHR. In the present paper, we explored the results of a newly designed partially absorbable mesh made of polypropylene and polylactic acid (HybridMesh) for open hernia repair and its impact on postoperative safety, efficacy, comfort and pain.

Methods: A prospective multicentric pilot trial was conducted in third-referral centers across Italy (n = 5).

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Over the last twenty years, segmental resection (SR) has been the technique most frequently used to treat bowel endometriosis. Nowadays, it is most commonly performed by laparoscopy; however, there is evidence that it can be safely performed by robotic-assisted laparoscopic surgery. Rectovaginal fistula and anastomotic leakage are the two major complications of SR; other complications include pelvic abscess, postoperative bleeding, ureteral damage, and anastomotic stricture.

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Objectives: Rectosigmoid involvement by endometriosis causes intestinal symptoms such as constipation, diarrhea, and dyschezia. A precise diagnosis about the presence, location, and extent of bowel implants is required to plan the most appropriate treatment. The aim of the study was to compare the accuracy of magnetic resonance with distension of the rectosigmoid (MR-e) with computed colonography (CTC) for diagnosing rectosigmoid endometriosis.

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