Publications by authors named "Srisupalak Singalavanija"
Atopic dermatitis (AD), a chronic, relapsing dermatitis, is characterized by dry and pruritus skin in patients with a personal or family history of atopy. It affects up to 20% of children and 1-3% of adults in most countries worldwide, and leads to significant treatment costs and morbidity. These guidelines are developed in accordance with evidence-based publications and expert opinions.
View Article and Find Full Text PDFClinical practice guideline for diagnosis and management of urticaria.
Asian Pac J Allergy Immunol
September 2016
Article Synopsis
- * A new guideline developed by various Thai medical associations provides evidence-based recommendations and algorithms to help physicians manage urticaria in both adults and children, emphasizing the importance of accurate diagnosis and treatment strategies.
- * First-line treatment for chronic spontaneous urticaria involves non-sedating H1-antihistamines, with options to increase dosage if necessary; alternative treatments like anti-IgE are available but may be costly, and lifestyle modifications are also suggested to reduce skin sensitivity.
Basidiobolus ranarum is an uncommon subcutaneous zygomycosis mostly found in immunocompetent children in tropical countries. Presence of slow growing non-tender, non-inflammatory, subcutaneous swelling that does not spread beyond the subcutaneous tissue are classic clinical features. The authors report two cases of subcutaneous zygomycosis which tissue cultures were positive for Basidiobolus ranarum.
View Article and Find Full Text PDFObjective: To study clinical manifestations, investigations, treatment and outcomes of neonatal lupus erythematosus (NLE) patients and their mothers.
Material And Method: A retrospective descriptive study was performed to review the neonatal lupus erythematosus patients and their mothers at Queen Sirikit National Institute of Child Health during January 1993 to December 2013. The diagnostic criteria required the presence of clinical symptoms plus positive anti-Ro/SSA or anti-La/SSB or both.
Objective: To analyze the clinical presentation and SLC39A4 mutations in zinc deficiency patients.
Material And Method: The authors conducted a cross-sectional study on all cases of zinc deficiency treated at Queen Sirikit National Institute of Child Health between January 2004 and December 2012. Demographic data, clinical manifestations, laboratory results, treatment and outcome were analyzed.
Randomized, double-blind, split-side, comparison study of moisturizer containing licochalcone A and 1% hydrocortisone in the treatment of childhood atopic dermatitis.
J Med Assoc Thai
September 2013
Background: Atopic dermatitis (AD) is a common chronic inflammatory skin lesion in children. Topical corticosteroid is the mainstay of treatment.
Objective: To compare the efficacy of moisturizer containing licochalcone A (LicA) and 1% hydrocortisone for the treatment of mild to moderate childhood AD.
Objective: To find out which of the clinical manifestations or laboratory findings is the predictive factor of severe renal involvement in children with Henoch-Schoenlein purpura (HSP).
Material And Method: Data of clinical manifestations and laboratory findings in children with HSP at Queen Sirikit National Institute of Child Health between January 2003-December 2007 were prospectively collected and analyzed.
Results: There were 168 cases, 86 boys and 82 girls (M:F ratio= 1.
Background: Stevens-Johnson syndrome (SJS) is a rare and severe life-threatening hypersensitivity syndrome. The etiology is unclear but is associated with drug exposure or infections and frequently high morbidity and mortality.
Objective: To determine etiologies, treatments and complications of Stevens-Johnson syndrome (SJS) in children.
Background: Mastocytosis is a disorder of mast cells proliferation within various organs, most commonly in the skin. The disease more commonly appears during infancy than adult.
Objective: To characterize the clinical features, response to therapy and prognosis of cutaneous mastocytosis in children.
Subcutaneous fat necrosis of the newborn (SCFN) is an uncommon disorder in full term infants who have a perinatal condition. The authors reported seven cases of subcutaneous fat necrosis of the newborn at Queen Sirikit National Institute of Child Health from 2002 to 2005. All cases were term babies with four male cases, and three female cases.
View Article and Find Full Text PDFIntroduction: This study evaluated the knowledge, attitudes and practices of Southeast Asian dermatologists in the management of atopic dermatitis (AD).
Materials And Methods: A questionnaire survey of 255 dermatologists in Indonesia, Malaysia, the Philippines, Singapore, Thailand and Vietnam.
Results: Familiarity with diagnostic criteria varied considerably.
Background: Severity of irritant diaper dermatitis (IDD) from diarrhea varies from patient to patient depending on the nature of feces and the number of bowel movements. The purpose of the present study was to compare the effectiveness of dexpanthenol and zinc oxide ointment with ointment base in the treatment of irritant diaper dermatitis from acute diarrhea in children by measuring transepidermal water loss (TEWL).
Material And Method: Forty-six children with diarrhea were prospectively, block randomized, investigator-blinded to receive dexpanthenol and zinc oxide ointment on one side and ointment base on the other side.
Background: Acquired immunobullous diseases in children are very rare and difficult to distinguish clinically.
Objective: To study the clinical manifestations, immunopathologic features, treatment and outcome of immunobullous diseases in Thai children.
Material And Method: The authors reviewed 24 cases of immunobullous diseases in children under 18 years at Queen Sirikit National Institute of Child Health from 1983 to 2000.
Background: Scabies is a common contagious skin disease in children. Treatment of scabies in infants and children is the subject of worldwide concern because of risk and benefit of the variety of scabicides.
Objective: To compare the efficacy of 10 per cent sulfur ointment and 0.