Publications by authors named "Srishti Kothari"
Purpose: To evaluate the incidence, remission, and relapse of post-surgical cystoid macular edema (PCME) following cataract surgery in inflammatory eye disease.
Methods: A total of 1859 eyes that had no visually significant macular edema prior to cataract surgery while under tertiary uveitis management were included. Standardized retrospective chart review was used to gather clinical data.
Article Synopsis
- A study evaluated the incidence of significant posterior capsule opacification (PCO) and YAG laser capsulotomy among uveitic eyes after cataract surgery, revealing that about 16% of eyes experienced PCO with reduced visual acuity within a year.* -
- Analysis of 1,855 uveitic eyes found that younger patients, those with poorer preoperative vision, and postoperative inflammation were more likely to develop PCO, while younger age and female sex were risk factors for needing YAG laser capsulotomy.* -
- The findings indicate that PCO is common in uveitic patients post-surgery, with 22% of eyes undergoing YAG laser treatment in the same timeframe, emphasizing the need for
Article Synopsis
- The study aimed to analyze the relationship between immunosuppression and overall as well as cancer-specific mortality in patients with noninfectious ocular inflammatory disease.
- Researchers examined data from over 15,000 patients over a median of 10 years and found there were 1970 deaths, with 435 attributed to cancer.
- The results indicated that patients on various immunosuppressants experienced similar mortality rates compared to the general U.S. population, suggesting that these treatments did not significantly increase overall or cancer mortality risk.
Purpose: To estimate the incidence/risk factors for cataract in noninfectious anterior uveitis.
Design: Retrospective multicenter cohort study (6 US tertiary uveitis sites, 1978-2010).
Methods: Data were harvested by trained expert reviewers, using protocol-driven review of experts' charts.
Purpose: To estimate the incidence of medication-free remission of chronic anterior uveitis and identify predictors thereof.
Design: Retrospective cohort study.
Participants: Patients diagnosed with anterior uveitis of longer than 3 months' duration followed up at United States tertiary uveitis care facilities.
Purpose: To describe the risk and risk factors for ocular hypertension (OHT) in adults with noninfectious uveitis.
Design: Retrospective, multicenter, cohort study.
Participants: Patients aged ≥18 years with noninfectious uveitis seen between 1979 and 2007 at 5 tertiary uveitis clinics.
Purpose: To evaluate the risk of and risk factors for retinal neovascularization (NV) in cases of uveitis.
Design: Retrospective cohort study.
Participants: Patients with uveitis at 4 US academic ocular inflammation subspecialty practices.
Purpose: To characterize the risk and risk factors for intraocular pressure (IOP) elevation in pediatric noninfectious uveitis.
Design: Multicenter retrospective cohort study.
Participants: Nine hundred sixteen children (1593 eyes) younger than 18 years at presentation with noninfectious uveitis followed up between January 1978 and December 2007 at 5 academic uveitis centers in the United States.
Ocular inflammatory disease is a leading cause of vision loss worldwide. Uveitis encompasses a wide spectrum of pathology, both with respect to its etiology and the anatomic location within the eye. Inflammation can be confined to the eye and may also be seen systemically.
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