Publications by authors named "Sriram Raju Dandu"
Nighttime agitation, sleep disturbances, and urinary incontinence (UI) occur frequently in individuals with dementia and can add additional burden to family caregivers, although the co-occurrence of these symptoms is not well understood. The purpose of the current study was to determine the feasibility and acceptability of using passive body sensors in community-dwelling individuals with Alzheimer's disease (AD) by family caregivers and the correlates among these distressing symptoms. A single-group, descriptive design with convenience sampling of participants with AD and their family caregivers was undertaken to address the study aims.
View Article and Find Full Text PDFUnderstanding the Physiological Significance of Four Inertial Gait Features in Multiple Sclerosis.
IEEE J Biomed Health Inform
January 2018
Article Synopsis
- - Gait impairment in multiple sclerosis (MS) is influenced by factors like muscle weakness, fatigue, and coordination issues, with walking speed often being the key indicator used by researchers.
- - The paper explores four inertial gait features captured by body-worn sensors to improve gait monitoring: the "DTW Score," "Warp Score," "KDE Peak," and "Causality Index," which utilize different algorithms for analysis.
- - By using factor analysis on common walking tests, the study reveals significant correlations between these inertial measures and walking-related symptoms, indicating that they offer distinct insights into the physiological aspects of MS-related walking disabilities.
Background: The six-minute walk (6MW) is a common walking outcome in multiple sclerosis (MS) thought to measure fatigability in addition to overall walking disability. However, direct evidence of 6MW induced gait deterioration is limited by the difficulty of measuring qualitative changes in walking.
Objectives: This study aims to (1) define and validate a measure of fatigue-related gait deterioration based on data from body-worn sensors; and (2) use this measure to detect gait deterioration induced by the 6MW.