Publications by authors named "Sriram Krishnamoorthy"

Article Synopsis
  • - Pheochromocytoma is a rare tumor that can show a variety of symptoms, making it easily overlooked, but timely diagnosis is crucial for treating associated high blood pressure and preventing serious health issues.
  • - Physicians need to be aware of the symptoms and diagnostic methods related to pheochromocytoma to avoid potentially fatal consequences from misdiagnosis.
  • - The study focuses on individual patient cases, their symptoms, diagnostic evaluations, and surgical outcomes while summarizing current literature and best practices for pheochromocytoma screening and diagnosis.
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Introduction: Retrograde intrarenal surgery (RIRS) is the standard treatment for renal calculi. Direct visualization and fragmentation are its major advantages. The variable stone clearance rates and the ergonomic challenges faced by urologists are a few limitations.

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Objective This study aims to identify the risk factors associated with postoperative complications following standard percutaneous nephrolithotomy (PCNL) for better results with the emergence of mini-percutaneous nephrolithotomy (mini-PCNL)/retrograde intrarenal surgery (RIRS) in recent years. Methodology This retrospective study was conducted in the Department of Urology, Sri Ramachandra Institute of Higher Education and Research, tertiary health care center in Chennai, India, from January 2018 to December 2023. Records of demographic information, along with clinical presentations like any urinary tract infection (UTI), hematuria, or loin pain were recorded.

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Wunderlich syndrome (WS), characterized by spontaneous nontraumatic renal or perinephric hemorrhage, presents a significant diagnostic challenge due to its varied causes and clinical manifestations. Despite its historically high case fatality rate, prompt and accurate diagnosis combined with a multidisciplinary treatment approach has been shown to significantly improve patient outcomes. This case series discusses three patients with diverse presentations of WS, each managed with tailored therapeutic strategies involving a combination of conservative management, super selective renal artery embolization, and surgical interventions such as nephrectomy.

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Penile injuries from self-inflicted strangulation or garroting are uncommon. Children are more likely than young adults or elderly patients to sustain such injuries. Numerous foreign things, including hair, thread, rubber bands, metallic rings, nuts, and vacuum erection devices, have been reported to be used for garroting in the literature search.

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Article Synopsis
  • Percutaneous nephrolithotripsy (PCNL) is the preferred method for treating large kidney stones, but can occasionally lead to rare complications like injuries to nearby organs, such as the gall bladder (GB).
  • A case was reported where a patient experienced GB perforation after PCNL, which was identified during the procedure when the surgeon noticed unusual fluid during the initial puncture.
  • The situation was addressed immediately with laparoscopic cholecystectomy, highlighting the importance of being aware of such complications for timely diagnosis and treatment to prevent serious outcomes.
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Circumcision is a commonly performed surgical procedure both in childhood and in adults. Acute ischemia of the glans penis after circumcision is a rare but hazardous complication. If left untreated, it can lead to severe consequences such as blackish discolouration due to ischemia, necrosis, or rare organ loss.

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Introduction: Benign prostatic hyperplasia (BPH) is a common urological condition, particularly among middle-aged and elderly men. Trans urethral resection of prostate (TURP) has some drawbacks, particularly concerning ejaculatory function. Ejaculation preserving TURP (Ep-TURP) is one such technique that aims at preserving the tissues that are primarily responsible for antegrade ejaculation.

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Tensor algebra operations such as contractions in computational chemistry consume a significant fraction of the computing time on large-scale computing platforms. The widespread use of tensor contractions between large multi-dimensional tensors in describing electronic structure theory has motivated the development of multiple tensor algebra frameworks targeting heterogeneous computing platforms. In this paper, we present Tensor Algebra for Many-body Methods (TAMM), a framework for productive and performance-portable development of scalable computational chemistry methods.

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Ultra-wide band gap semiconductor devices based on β-phase gallium oxide (GaO) offer the potential to achieve higher switching performance and efficiency and lower manufacturing cost than that of today's wide band gap power electronics. However, the most critical challenge to the commercialization of GaO electronics is overheating, which impacts the device performance and reliability. We fabricated a GaO/4H-SiC composite wafer using a fusion-bonding method.

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Article Synopsis
  • Genome assembly is a key challenge in computational molecular biology, aiming to reconstruct genomes from short DNA sequences known as reads, where their order is critical to the assembly process.
  • The article introduces BOA (bucket-order-assemble), a method that leverages bucketing and partitioning techniques to create a partial order of reads, facilitating independent assembly of disjoint blocks in parallel.
  • Experimental results indicate that BOA enhances both the quality of genome assemblies and the efficiency of the assembly process.
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While quantum algorithms for simulations exhibit better asymptotic scaling than their classical counterparts, they currently cannot be accurately implemented on real-world devices. Instead, chemists and computer scientists rely on costly classical simulations of these quantum algorithms. In particular, the quantum phase estimation (QPE) algorithm is among several approaches that has attracted much attention in recent years due to its genuine quantum character.

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Rapid diagnostic card tests (RDTs) enable timely and appropriate diagnosis of malaria especially in remote areas. histidine rich protein 2 (PFHRP2) is the most targeted antigen for the detection of infections by rapid diagnostic card test. Genetic mutations and gene deletions are important emerging factors for false-negative RDTs, which may delay the provision of life-saving treatment for the patients.

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Monoclinic β-GaO, an ultra-wide bandgap semiconductor, has seen enormous activity in recent years. However, the fundamental study of the plasmon-phonon coupling that dictates electron transport properties has not been possible due to the difficulty in achieving higher carrier density (without introducing chemical disorder). Here, we report a highly reversible, electrostatic doping of β-GaO films with tunable carrier densities using ion-gel-gated electric double-layer transistor configuration.

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In this work, a systematic photoluminescence (PL) study on three series of gallium oxide/aluminum gallium oxide films and bulk single crystals is performed including comparing doping, epitaxial substrates, and aluminum concentration. It is observed that blue/green emission intensity strongly correlates with extended structural defects rather than the point defects frequently assumed. Bulk crystals or Si-doped films homoepitaxially grown on (010) β-GaO yield an intense dominant UV emission, while samples with extended structural defects, such as gallium oxide films grown on either (-201) β-GaO or sapphire, as well as thick aluminum gallium oxide films grown on either (010) β-GaO or sapphire, all show a very broad PL spectrum with intense dominant blue/green emission.

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Objectives: Post-transurethral resection of prostate urethral stricture (PTS) is a well-documented delayed complication following transurethral resection of the prostate (TURP). The aim is to analyze various risk factors of PTS and see if the overall incidence is underreported.

Materials And Methods: A retrospective study was conducted in our institution between January 2017 and December 2018 in men who underwent TURP.

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Extrauterine endometrial stromal sarcomas (EUESSs) are rare tumours occurring without primary uterine involvement. They are classified as primary or secondary, depending on uterine involvement by stromal sarcomas. A 56-year-old woman who earlier underwent bilateral modified radical mastectomy for adenocarcinoma and total abdominal hysterectomy for endometrial stromal sarcoma, followed by tamoxifen therapy, presented with left loin pain.

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Heterogeneous integration strategies are increasingly being employed to achieve more compact and capable electronics systems for multiple applications including space, electric vehicles, and wearable and medical devices. To enable new integration strategies, the growth and transfer of thin electronic films and devices, including III-nitrides, metal oxides, and 2D materials, using 2D boron nitride (BN)-on-sapphire templates are demonstrated. The van der Waals (vdW) BN layer, in this case, acts as a preferred mechanical release layer for precise separation at the substrate-film interface and leaves a smooth surface suitable for vdW bonding.

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β-phase gallium oxide (GaO) is an emerging ultrawide bandgap (UWBG) semiconductor ( ∼ 4.8 eV), which promises generational improvements in the performance and manufacturing cost over today's commercial wide bandgap power electronics based on GaN and SiC. However, overheating has been identified as a major bottleneck to the performance and commercialization of GaO device technologies.

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Heteroepitaxy of β-phase gallium oxide (β-GaO) thin films on foreign substrates shows promise for the development of next-generation deep ultraviolet solar blind photodetectors and power electronic devices. In this work, the influences of the film thickness and crystallinity on the thermal conductivity of (2̅01)-oriented β-GaO heteroepitaxial thin films were investigated. Unintentionally doped β-GaO thin films were grown on -plane sapphire substrates with off-axis angles of 0° and 6° toward ⟨112̅0⟩ via metal-organic vapor phase epitaxy (MOVPE) and low-pressure chemical vapor deposition.

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Forniceal ruptures after acute pyelonephritis are relatively common. Bilateral spontaneous subcapsular haematoma (SSCH) is an uncommon sequela to pyelonephritis. We report a case of SSCH where the underlying cause of haematoma was a vascular anomaly.

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Since the advent of the first computers, chemists have been at the forefront of using computers to understand and solve complex chemical problems. As the hardware and software have evolved, so have the theoretical and computational chemistry methods and algorithms. Parallel computers clearly changed the common computing paradigm in the late 1970s and 80s, and the field has again seen a paradigm shift with the advent of graphical processing units.

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This paper explores the utility of the quantum phase estimation (QPE) algorithm in calculating high-energy excited states characterized by the promotion of electrons occupying core-level shells. These states have been intensively studied over the last few decades, especially in supporting the experimental effort at light sources. Results obtained with QPE are compared with various high-accuracy many-body techniques developed to describe core-level states.

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Article Synopsis
  • The study aimed to define features and prognostic factors for patients with emphysematous pyelonephritis (EPN), ultimately developing a scoring system to enhance management outcomes.
  • Conducted between January 2009 and December 2019, the research included 131 patients, categorizing them based on survival and intervention type while analyzing various predictive factors through imaging and lab results.
  • Key findings indicated that factors like diabetes and shock upon admission were significantly linked to poor outcomes, emphasizing the importance of early diagnosis and targeted treatment for better patient care in EPN cases.
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Cancer is the second leading cause of death worldwide, with prostate cancer, the second most commonly diagnosed cancer among men. Prostate cancer develops in the peripheral zone of the prostate gland, and the initial progression largely depends on androgens, the male reproductive hormone that regulates the growth and development of the prostate gland and testis. The currently available treatments for androgen dependent prostate cancer are, however, effective for a limited period, where the patients show disease relapse, and develop androgen-independent prostate cancer (AIPC).

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