Describing the Structural Phenotype of the Glaucomatous Optic Nerve Head Using Artificial Intelligence.

Purpose: To develop a novel deep-learning approach that can describe the structural phenotype of the glaucomatous optic nerve head (ONH) and can be used as a robust glaucoma diagnosis tool.

Design: Retrospective, deep-learning approach diagnosis study.

Method: We trained a deep-learning network to segment 3 neural-tissue and 4 connective-tissue layers of the ONH.