Publications by authors named "Srinivas Melpakkam"

Background Individuals working in the information technology (IT) industry are likely to develop lifestyle disorders. We aimed to determine the presence of defaecation-related disorders in IT personnel in Chennai. Methods This cross-sectional, questionnaire-based study was done from June to December 2018.

View Article and Find Full Text PDF

Background: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late.

Aim: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting.

Materials And Methods: This retrospective study included all patients diagnosed with achalasia cardia on high-resolution esophageal manometry, using Chicago Classification v 3.

View Article and Find Full Text PDF

Background/aims: Consensus guidelines for performance and analysis of high-resolution esophageal manometry (HREM) recommend use of equipment, population and posture specific normative values. To provide normative values for Chicago classification (CC) metrics in the physiological seated position for a 16-channel water perfused system (Dentsleeve HREM catheter, Advanced Manometry Systems, Melbourne, Australia) widely used in India and other countries with limited access to solid-state equipment. The results are compared with published CC metrics in supine position done using the same system and volunteers.

View Article and Find Full Text PDF

Background: There is paucity of data on Bristol stool form (BSF) in healthy South Indian residents.

Aim: To determine the BSF types and associated factors in an urban bowel health noncomplainant population.

Methods: This cross-sectional study, performed using a self-administered questionnaire among adult Chennai residents, compared BSF types by gender for various factors (age, occupation, bowel frequency, and defecation-related abdominal pain).

View Article and Find Full Text PDF

Patients with gastroesophageal reflux disease are commonly referred to a gastrointestinal motility unit for assessment of esophageal physiology tests prior to an anti-reflux procedure. On esophageal manometry, most patients have normal peristalsis; however, minor disorders of motility such as ineffective esophageal motility and fragmented peristalsis are not uncommon. Multiple rapid swallow (MRS) test is a provocative method for assessing peristaltic reserve in such patients.

View Article and Find Full Text PDF

Background: There is insufficient data from India regarding clinical predictors of dyssynergic defecation.

Aim: To identify demography, symptom, and colonoscopic parameters that can predict dyssynergic defecation (DD) among patients with chronic constipation (CC) and to compare the profile among male and female patients with DD.

Methods: Data collected from three centers during June 2014 to May 2017 included age, gender, symptom duration, form and consistency of stools, digital examination, colonoscopy, and anorectal manometry (ARM).

View Article and Find Full Text PDF

Aim: To assess the correlation of symptoms with findings on esophageal high-resolution manometry (HRM) in Indian patients.

Materials And Methods: Prospective data collection of all patients undergoing esophageal manometry was done at two centers in India-Indore and Chennai-over a period of 18 months. Symptom profile of the study group was divided into four: Motor dysphagia, noncardiac chest pain (NCCP), gastroesophageal reflux (GER), and esophageal belchers.

View Article and Find Full Text PDF

Background & Aims: Celiac disease shares features of other disorders. It can be diagnosed conclusively only based on duodenal histology analysis, which is not practical for screening purposes. Serologic analysis might be used to identify candidates for biopsy analysis.

View Article and Find Full Text PDF

Aim: To identify risk factors for common bile duct (CBD) stones in a south Indian population.

Methods: Demographic characteristics and diet details were obtained from patients with isolated CBD stones (Gp I) and those with combined CBD and gallstones (Gp II) and age- and sex-matched controls. The risk factors were compared between the two groups.

View Article and Find Full Text PDF