Profiling of urinary proteins in Karan Fries cows reveals more than 1550 proteins.

Urine is a non-invasive source of biological fluid, which reflects the physiological status of the mammals. We have profiled the cow urinary proteome and analyzed its functional significance. The urine collected from three healthy cows was concentrated by diafiltration (DF) followed by protein extraction using three methods, namely methanol, acetone, and ammonium sulphate (AS) precipitation and Proteo Spin urine concentration kit (PS).

Susceptibility of bacterial isolates to vancomycin and ceftazidime from patients with endophthalmitis: Is there a need to change the empirical therapy in suspected bacterial endophthalmitis?

To review the susceptibility of bacterial isolates to ceftazidime and vancomycin isolated from patients with endophthalmitis. Microbiology records of patients with endophthalmitis between June 2010 and May 2013 were reviewed. Vitreous and AC fluids obtained from patients with endophthalmitis were subjected to direct microscopy examination and culture.

Clinical and microbiologic review of culture-proven endophthalmitis caused by multidrug-resistant bacteria in patients seen at a tertiary eye care center in southern India.

Purpose: To determine the type of bacteria and the visual outcome of culture-proven multidrug-resistant bacterial endophthalmitis in patients at a tertiary eye care center in southern India.

Methods: This is a retrospective case series in which clinical and microbiologic records of culture-proven bacterial endophthalmitis between January 2000 and December 2007 were reviewed. Multidrug resistance was defined as resistance to two or more different groups of typically susceptible classes of antibiotics.

Spontaneous bilateral subhyaloid hemorrhage in congenital hypofibrinogenemia.

Purpose: The purpose of this study was to report a case of spontaneous bilateral subhyaloid hemorrhage in congenital hypofibrinogenemia.

Methods: This is a single case report. A 14-year-old girl presented with a spontaneous bilateral decrease in vision.

Presumed metastasis of choroidal melanoma to the contralateral choroid.

Purpose: To report a case of choroidal melanoma metastasizing to contralateral choroid along with systemic metastasis.

Methods: This is a retrospective study of a case of a 52-year-old man who was found to have a choroidal lesion in the left eye temporal to fovea. The ultrasound and angiographic findings were suggestive of choroidal melanoma, which prompted enucleation of the eye.

Evaluation of vitreous levels of gatifloxacin after systemic administration in inflamed and non-inflamed eyes.

Purpose: This study aimed to evaluate the human vitreous penetration of gatifloxacin in inflamed and non-inflamed eyes after oral administration.

Methods: Vitreous penetration of single-dose (400 mg) oral gatifloxacin was evaluated in patients (n = 33) undergoing vitreous tap during the standard procedure for intravitreal antibiotic injection for acute postoperative endophthalmitis at various time-points. Vitreous penetration of 400 mg oral gatifloxacin was evaluated in the non-inflamed eyes of patients (n = 33) undergoing pars plana vitrectomy at similar time-points.