The evidence and prevalence of multidrug-resistant (MDR) spp. poses a serious global threat to public health and the economy. Food- or water-borne MDR spp.
View Article and Find Full Text PDFRenewable natural gas (RNG) sources are being considered in future energy strategy discussions as potential replacements for fossil natural gas (FNG). While today's supply of RNG resources is insufficient to meet U.S.
View Article and Find Full Text PDFChicken kidney (CK) cells have been widely utilized in virus research studies for many years. The optimized technique of primary CK cell culture production involving both mechanical and enzymatic disaggregation is described. This updated method proved to consistently give high cell yields and resultant cultures are readily used for virus assays.
View Article and Find Full Text PDFThe risk of venous thromboembolism (VTE) is increased in patients with cancer. However, the role of tumor markers as potential indicators of increased risk of VTE is still undetermined. In this retrospective observational case control study, levels of the tumor markers CEA, CA 19-9 and CA 125 in patients with colorectal, pancreatic, and ovarian cancer respectively, who were admitted to two community hospitals between January 2001 and December 2011, were compared between patients who were VTE positive and those who were VTE negative.
View Article and Find Full Text PDFBackground: Arrest of metastasising lung cancer cells to the brain microvasculature maybe mediated by interactions between ligands on circulating tumour cells and endothelial E-selectin adhesion molecules; a process likely to be regulated by the endothelial glycocalyx. Using human cerebral microvascular endothelial cells and non-small cell lung cancer (NSCLC) cell lines, we describe how factors secreted by NSCLC cells i.e.
View Article and Find Full Text PDFContext: There are no established guidelines for the proper treatment of patients with bronchopleural fistulas (BPFs). Apart from attempts to close the fistula, emphasis of treatment and management is placed on preventive measures, early administration of antibiotics, drainage of the empyema and aggressive nutritional and rehabilitative support.
Case Report: A 53-year-old male presented with nausea, vomiting, and dry cough with eventual respiratory failure.
Epithelial ovarian cancer (EOC) metastasizes transcoelomically to the peritoneum and omentum, and despite surgery and chemotherapy, recurrent disease is likely. Metastasis requires the induction of proangiogenic changes in the omental microenvironment and EOC-induced omental angiogenesis is currently a key therapeutic target. In particular, antiangiogenic therapies targeting the vascular endothelial growth factor A (VEGFA) pathway are commonly used, although, with limited effects.
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