ECG biomarkers for simultaneous detection of obstructive sleep apnea and Cheyne-Stokes breathing.

Use of extended electrocardiography (ECG) for detection of sleep disordered breathing SDB when obstructive sleep apneas and Cheyne-Stokes breathing are simultaneously present is explored. A multi-tier algorithm is designed that uses quantitative changes in the morphology of the QRS complex of Lead 1 and V4 due of SDB events and combines those changes with variations in heart rate to detect each type of SDB. For this purpose, ECG signals are divided into 15 minute epochs.

Classification of Cheyne-Stokes breathing and obstructive sleep apnea using ECG.

High cost of diagnostic studies to detect sleep disordered breathing and lack of availability of certified sleep laboratories in all inhabited areas make investigation of alternative methods of detecting sleep disordered breathing attractive. This study aimed to explore the possibility of discerning obstructive sleep apnea (OSA) from Cheyne-Stokes respiration (CSR) using overnight electrocardiography (ECG). Polysomnographic and ECG signals were acquired from the 13 OSA and 7 CSR volunteer subjects.

Spectral analysis of R wave attenuation and heart rate variability for detection of cheyne stokes breathing.

Spectral analysis was carried out on the R-Wave Attenuation (RWA) trend and Heart Rate Variability (HRV) series, derived from the polysomnographic Electrocardiogram (ECG) of the subjects with and without Cheyne Stokes Breathing. Nocturnal polysomnography was performed on 16 Normal subjects and 7 subjects with Cheyne Stokes Breathing (CSB) patients. The polysomnographic ECG data was divided into fifteen minute epochs for analysis.

Time domain analysis of R-wave attenuation envelope for sleep apnea detection.

Time domain analysis was carried out on the R-wave attenuation (RWA) envelope of the subjects with and without obstructive sleep apnea. The RWA envelope is derived from the morphology of the electrocardiogram (ECG) obtained during polysomnography data collection of the subjects. Nocturnal polysomnography was performed on 16 normal subjects and 14 obstructive sleep apnea (OSA) patients.