Monte Carlo-based dosimetry of proposed bi-radionuclide (I and Ru/Rh) eye plaque: A feasibility study.

Background: Combining the sharp dose fall off feature of beta-emitting Ru/Rh radionuclide with larger penetration depth feature of photon-emittingI radionuclide in a bi-radionuclide plaque, prescribed dose to the tumor apex can be delivered while maintaining the tumor dose uniformity and sparing the organs at risk. The potential advantages of bi-radionuclide plaque could be of interest in context of ocular brachytherapy.

Purpose: The aim of the study is to evaluate the dosimetric advantages of a proposed bi-radionuclide plaque for two different designs, consisting of indigenous I seeds and Ru/Rh plaque, using Monte Carlo technique.

Monte Carlo-based dosimetric studies of a locally developedTm LDR brachytherapy seed source.

Tm is being explored as a source for applications in brachytherapy. Although it has adequate physical properties, such as a short half-life (128.6 d), high specific activity and a mean photon energy of about 66 keV, it has a drawback of low photon yield (only about six photon emissions/100 beta emissions).

Dosimetry of indigenously developed Lu patch source for surface brachytherapy-Experimental and Monte Carlo methods.

This paper describes the evaluation of dosimetry characteristics of an in-house developed Lu skin patch source for treatment of non-melanoma skin cancer. A Lu skin patch source based on Nafion-115 membrane backbone containing 3.46 ± 0.

Dosimetry of indigenously developed (192)Ir high-dose rate brachytherapy source: An EGSnrc Monte Carlo study.

Clinical application using high-dose rate (HDR) (192)Ir sources in remote afterloading technique is a well-established treatment method. In this direction, Board of Radiation and Isotope Technology (BRIT) and Bhabha Atomic Research Centre, India, jointly indigenously developed a remote afterloading machine and (192)Ir HDR source. The two-dimensional (2D) dose distribution and dosimetric parameters of the BRIT (192)Ir HDR source are generated using EGSnrc Monte Carlo code system in a 40 cm dia × 40 cm height cylindrical water phantom.

Monte Carlo-based dose calculation for (32)P patch source for superficial brachytherapy applications.

Skin cancer treatment involving (32)P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed (32)P nafion-based patch source (1 cm × 1 cm) for treating skin cancer. For this source, the values of dose per unit activity at different depths including dose profiles in water are calculated using the EGSnrc-based Monte Carlo code system.

Monte Carlo-based investigation of water-equivalence of solid phantoms at (137)Cs energy.

Investigation of solid phantom materials such as solid water, virtual water, plastic water, RW1, polystyrene, and polymethylmethacrylate (PMMA) for their equivalence to liquid water at (137)Cs energy (photon energy of 662 keV) under full scatter conditions is carried out using the EGSnrc Monte Carlo code system. Monte Carlo-based EGSnrc code system was used in the work to calculate distance-dependent phantom scatter corrections. The study also includes separation of primary and scattered dose components.

An analytic approach to the dosimetry of a new BEBIG (60)Co high-dose-rate brachytherapy source.

We present a simple analytic tool for calculating the dose rate distribution in water for a new BEBIG high-dose-rate (HDR) (60)Co brachytherapy source. In the analytic tool, we consider the active source as a point located at the geometric center of the (60)Co material. The influence of the activity distribution in the active volume of the source is taken into account separately by use of the line source-based geometric function.

An EGSnrc investigation of the air-kerma strength, dose rate constant, and radial dose function of 125I brachytherapy sources.

Titanium-encapsulated (125)I brachytherapy sources are in use for treatment of the eye, brain, and head and neck region, and for early stage prostate cancer. The photoelectric interaction of (125)I photons with titanium encapsulation generates Ti K X-rays (approximately 5 keV). According to the National Institute of Standards and Technology (NIST) 1999 air-kerma strength, S(k), standard, these X-rays should be excluded from S (k).