Publications by authors named "Sridhar Karne"
The acetabular triradiate cartilage is the main structure that determines the development of the acetabulum. Furthermore, the paucity of data in the literature and lack of consensus amongst physicians following diagnosis regarding whether to treat these fractures operatively or non-operatively places the physician with a challenging choice. Here, we report a case of a 13-year-old boy who suffered a triradiate cartilage fracture from a high-energy motorcycle crash and presented with a displaced, left T-type acetabulum fracture.
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- The transition of the US Medical Licensing Examination Step 1 to a pass/fail format has heightened the significance of research experience for medical students applying to neurosurgery residency, particularly for those from schools without a dedicated neurosurgery program.
- From 2016 to 2022, the number of applicants from such schools matched in neurosurgery increased initially, then slightly declined, with median publications per resident significantly rising during that period.
- There were notable differences in the h-index between applicants who matched into top 40 programs compared to others, suggesting that research productivity may play a role in residency selection, even if overall publication numbers alone did not show significant differences.
Background: Macromastia, defined as the abnormal enlargement of breasts, burdens individuals physically and psychologically, impacting their daily lives beyond aesthetics. Reduction mammoplasty offers relief by restoring proportional breast volume and appropriate contour. Surgical success relies on choosing a suitable individualized operative technique tailored to the patient's presentation and postoperative goals.
View Article and Find Full Text PDFThe 1.6-megabase deletion at chromosome 3q29 (3q29Del) is the strongest identified genetic risk factor for schizophrenia, but the effects of this variant on neurodevelopment are not well understood. We interrogated the developing neural transcriptome in two experimental model systems with complementary advantages: isogenic human cortical organoids and isocortex from the 3q29Del mouse model.
View Article and Find Full Text PDFRecent advances in the genetics of schizophrenia (SCZ) have identified rare variants that confer high disease risk, including a 1.6 Mb deletion at chromosome 3q29 with a staggeringly large effect size (O.R.
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