Publications by authors named "Sricharvi Mannam"
Langerhans cell histiocytosis (LCH) is a complex disorder characterized by the clonal proliferation of Langerhans cells, primarily affecting children and adolescents. This condition exhibits a wide spectrum of clinical presentations, necessitating a multidisciplinary approach for diagnosis, treatment, and follow-up. Cutaneous manifestations of LCH are significant, mimicking common dermatoses and posing diagnostic challenges.
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- Glioblastomas (GBM) are aggressive brain tumors with poor outcomes, prompting the need for new treatment approaches like dendritic cell vaccinations (DCVs).
- Although early trials show some promise in boosting the immune response against tumors, results are inconsistent, influenced by various trial-specific factors.
- The review examines how DCVs work, evaluates past clinical trials, and suggests future strategies to improve GBM treatment by combining DCVs with traditional therapies.