Corrigendum: Unveiling barriers to reproductive health awareness among rural adolescents: a systematic review.

[This corrects the article DOI: 10.3389/frph.2024.

Antimetastatic effect of nanodiamond-conjugated quercetin against colon cancer: an in vivo study.

Background/aim: Quercetin (Q) is a compound that can inhibit the growth of cancer cells in the colon; however, to do so, a high dose is needed, requiring a drug delivery system to target cancer endothelial cells directly. This study investigates the potency of nanodiamond-conjugated quercetin (NDQ) as an anticancer drug against colon cancer in induced by N-methyl N-Nitrosourea (MNU).

Materials And Methods: This study is experimental-based and was designed using a six-group treatment method, namely normal control (KN: not treated by MNU, nanodiamond (ND), or Q); negative control (K-: treated by MNU); positive control (K+: treated by MNU and capecitabine); ND (treated by MNU and NDs); Q (treated by MNU and Q); and NDQ (treated by MNU and NDQ).

fruit extract as a potential antioxidant against liver injury by 2-Nitropropane induction in obese male mice model: pre-clinical study.

fruit extract contains beneficial chemical compounds. This study was conducted to observed the power of antioxidant against liver injury by 2-Nitropropane induction in an obese male mice model. This research was laboratory experimental study with a post-test control design group only.

Supplementation of and to increase growth performance and immune system of catfish () due to infection.

Background And Aim: Catfish has a high economic value and is popular among consumers. To ensure well-stocked catfish stocks, good fisheries management must also be ensured. The high demand for catfish must be supplemented by preventive measures against pathogenic bacterial infections using probiotics with high potential for and .

Factors Associated with Improving Appropriate Medical Sharps Disposal Practice Among Diabetic Patients Using Insulin Therapy.

Background: Diabetic patients are always in contact with medical sharps, such as pen needles, lancets, and syringes. Sometimes, patients improperly dispose of these items and cause needle stick injuries. This study aimed to identify factors that improve appropriate manner in which individuals with diabetes who require insulin therapy dispose of medical sharps.

The Effect of Crude Polysaccharide Extract on Proinflammatory Cytokines and Proapoptotic Caspases in HeLa Cell Line: An Study.

Polysaccharide extracts exhibit promise as potential anticancer agents. Among the fungi rich in polysaccharide content, stands out; however, its anticancer activity necessitates further investigation. This study aims to explore the impact of crude polysaccharide (GACP) extract by assessing its effects on cell viability, levels of proinflammatory cytokines such as TNF-, IFN-, IL-2, and IL-12, and levels of proapoptotic markers including caspase-3 and caspase-9, as well as the percentages of necrosis and apoptosis in the HeLa cell line.

Enhancing skill conceptualization, critical thinking, and nursing knowledge through reflective case discussions: a systematic review.

Reflective case discussion (RCD) is a reflective activity conducted by nurses, midwives, and other healthcare workers to enhance their skills, critical thinking, and knowledge. This systematic review follows the PRISMA Guideline checklist and includes articles from various databases, such as Scopus, PubMed, ProQuest, and ScienceDirect. The quality assessment of each article was performed using the Critical Appraisal Skills Program (CASP).

Effectiveness of ozone-laser photodynamic combination therapy for healing wounds infected with methicillin-resistant in mice.

Background And Aim: According to 2013 data from the Ministry of Health of the Republic of Indonesia, there were 8.2% more wounds than typical in Indonesia; 25.4% were open wounds, 70.

The use of cellulolytic sp. inoculum to improve the quality of Pineapple compost.

Pineapple litter has a complex polymer of cellulose, hemicellulose, and lignin, which makes them difficult to decompose. However, pineapple litter has great potential to be a good organic material source for the soil when completely decomposed. The addition of inoculants can facilitate the composting process.

Increasing the effect of annonacin using nanodiamonds to inhibit breast cancer cells growth in rats ()-Induced breast cancer.

Background: Annonaceous acetogenins have been reported to have anti-cancer properties but low viability. In this study, we aimed to investigate the potency of nanodiamonds to be employed as a carrier of annonacin to help increase its viability and inhibit the growth of breast cancer cells.

Methods: The annonacin was coupled with nanodiamond and characterized using UV-Vis spectrophotometer, FTIR, SEM, and PSA, and determined their stability and drug release.

The Regulation of Hypoxia Inducible Factor (HIF)1α Expression by Quercetin: an In Silico Study.

Background: Cancer disease is a growing health problem in developing and developed countries. Hypoxia-inducible factor-1a (HIF1α) is a transcription factor responsible for expressing several proteins involved in angiogenesis. Quercetin can suppress HIF1α expression due to the inhibition of protein synthesis.

Anti-cancer activity of an ethanolic extract of red okra pods ( L. Moench) in rats induced by -methyl-nitrosourea.

Background And Aim: Breast cancer is the most frequent malignancy in women. The consumption of phytochemical components from plants may play an essential role in preventing and treating this cancer. This study aimed to investigate the anti-cancer activity of an ethanolic extract of red okra pods (EEROP) in rats () induced by -methyl- -nitrosourea (MNU).

Effect of crude polysaccharides as a renoprotective agent against carbon tetrachloride-induced early kidney fibrosis in mice.

Background And Aim: Interstitial fibrosis is the final stage of chronic kidney injury, which begins with an inflammatory process. Crude polysaccharides are known to have anti-inflammatory properties. The potential role of crude polysaccharides in renal fibrosis through pro-inflammatory cytokines needs further investigation.

Effect of the Ethanol Extract of Red Okra Pods ( (L.) Moench) to Inhibit Cervical Cancer Cells Growth through Cell Cycle-Associated Oncogenes.

This study aims to evaluate the potency of ethanol extract of red okra pods (EEROP) in inhibiting growth of cervical cancer cells through repression of the cell cycle-associated oncogenes. The EEROP treatment was given to HeLa cells cultured with RPMI medium and incubated at 37°C with 5% CO. The MTT method was used to measure HeLa cell growth and IC values.

The role of work stress, organizational climate, and improving employee performance in the implementation of work from home.

Background: The spread of COVID-19 around the world has caused many undesirable effects on human health. The pandemic forced the employees to resort to Remote Work (RW)/Work from Home (WFH) according to the nature of the jobs. Consequently, organizations, business process and results are affected and organizational and commercial activities are significantly reduced.

The potential of A. Muricata Bioactive Compounds to Inhibit HIF1α Expression Via Disruption of Tyrosine Kinase Receptor Activity: an In Silico Study.

Background: Cancer is a debilitating disease that is on the increase in both developed and developing countries. The plant extract of have been known to have a variety of anticancer effects, including anti-angiogenic potential. An in silico study is needed as a preliminary study to understand the mechanism underline this process.

Protective Effect of Red Okra ( (L.) Moench) Pods against Sodium Nitrite-Induced Liver Injury in Mice.

Vegetables, drinking water, and preserved meats may contain sodium nitrite (NaNO), which causes liver disease by inducing oxidative stress. Phytochemicals are highly recommended as an alternative to synthetic drugs and affordable medicines to treat liver disease because they have fewer or no side effects. Therefore, this study aims to determine the antioxidant and hepatoprotective potential of red okra fruit ethanol extract against NaNO-induced liver damage.

Dual role of immunomodulation by crude polysaccharide from okra against carcinogenic liver injury in mice.

Polysaccharides have long been recognized as the anticancer agent with low toxicity and slight side effects. Okra ( L.), a flowering plant from the Malvaceae family that is found in tropical, subtropical, and warm temperate regions around the world.

Hepatoprotective activity of okra ( L.) in sodium nitrite-induced hepatotoxicity.

Background And Aim: For years, people have used sodium nitrite as a food preservative. This study determined the effect of okra ( L.) pod methanol extract (OPME) on mice with hepatotoxicity induced by sodium nitrite.

Antioxidant and Nephroprotective Effects of Okra Pods Extract ( L.) against Lead Acetate-Induced Toxicity in Mice.

In this study, we determine the curative effects of okra pods ( L.) extract against lead acetate toxicity in mice kidney. -Hexane, ethyl acetate, and methanol solvent were used for extracting okra pods.

Hepatoprotective effect of crude polysaccharides extracted from against carbon tetrachloride-induced liver injury in mice.

Background And Aim: Natural products are currently widely used as alternative treatments for liver disease. The study aimed to determine the hepatoprotective effect of crude polysaccharides extracted from against liver injury induced by carbon tetrachloride (CCl).

Materials And Methods: Twenty-four male BALB/C mice were randomly divided into six groups.

Immunomodulatory potential of polysaccharides from against intracellular bacteria .

Background And Aim: For many years, people use natural products from the plant and fungal to improve immune response against microorganism. This study aimed to investigate the immunomodulatory properties of polysaccharides (PS) from in mice infected by intracellular bacteria .

Materials And Methods: Thirty-six female BALB/C mice were divided into six groups: Normal control, negative control, positive control, P1 (PS before infection), P2 (PS after infection), and P3 (PS before and after infection).

Crude Polysaccharides from Okra Pods () Grown in Indonesia Enhance the Immune Response due to Bacterial Infection.

Okra pods were widely consumed by Indonesians to maintain health. The aim of this study was at investigating the potential of crude polysaccharides from okra pods on immune response in mice infected with Thirty male Balb/C mice were divided into six groups: normal control, negative control, and treatment groups (administration of crude polysaccharides at doses of 25, 50, 75, and 100 mg/kg). Crude polysaccharides were administrated for fourteen days.