Optimized Methods to Quantify Tumor Treating Fields (TTFields)-Induced Permeabilization of Glioblastoma Cell Membranes.

Glioblastoma (GBM) is a lethal primary brain cancer with a 5.6% five-year survival rate. Tumor treating fields (TTFields) are alternating low-intensity electric fields that have demonstrated a GBM patient survival benefit.

The Psychology Behind the Efficacy of a Buddy System for Enhancing Retention in Dermatological Clinical Trials.

Retention in dermatological clinical trials is critical for ensuring the validity and reliability of study outcomes, yet participant dropout remains a pervasive challenge. In this analysis, the primary aim is to explore the psychological mechanisms underpinning the efficacy of a buddy system in enhancing retention rates in such trials. The buddy system, where participants are paired with peers who have previously participated in similar clinical trials offers mutual support and leverages the principles of social bonding, accountability, and shared experience to foster commitment and reduce attrition.