Publications by authors named "Sri Agustini Kurniawati"
Article Synopsis
- Advances in molecular biology and high-throughput tests are enhancing lung cancer management by identifying genetic variations in patients.* -
- A study analyzing 627 tissue samples and 80 liquid biopsy samples from lung cancer patients revealed various EGFR variants using RT-PCR and next-generation sequencing (NGS).* -
- The results indicated that EGFR variants are prevalent, and liquid biopsy with ctDNA can uncover a wider range of genetic variations, which is crucial for tailoring treatment plans.*
Background: Brain metastases are a common complication in a wide range of cancers but are ubiquitous among patients with lung cancer. Limited data are available on the survival of patients with lung cancer and brain metastases in Indonesia. In this study, we aimed to identify the factors that might contribute to and predict survival in patients with non-small cell lung cancer (NSCLC) that resulted in brain metastases.
View Article and Find Full Text PDFArticle Synopsis
- Most patients with advanced non-small cell lung cancer (NSCLC) have a poor survival rate, and the study investigates how nutritional status impacts treatment response and overall survival in these patients.
- The study followed 174 patients with stage II-IV NSCLC over two years, revealing that only a small percentage achieved a complete response to treatment, and the median survival was 12 months.
- Findings indicated that being male and overweight or obese are linked to lower survival rates, regardless of other factors like age, disease stage, and baseline health.
Article Synopsis
- This study investigates the potential of the FIB-4 index as a predictor of mortality in patients with both hematological malignancies and COVID-19, focusing on finding an optimal cut-off value.
- Conducted at Dharmais National Cancer Hospital in Indonesia, it analyzed 70 patients and found a significant correlation between higher FIB-4 values and increased mortality risk over a 3-month period.
- The results indicated that a FIB-4 index greater than 3.85 had strong predictive power for mortality, with implications for patient management and treatment decisions.
Article Synopsis
- The study investigates survival factors in elderly cancer patients in Indonesia, focusing on those over 60 years old, due to the increasing elderly population and cancer prevalence.
- Conducted as a retrospective cohort study with 249 patients, it analyzed various clinical factors such as age, cancer type, and treatment to determine their impact on survival.
- Results revealed that advanced cancer stage significantly affects mortality in women, while poor performance status is a key risk factor for men, highlighting the importance of these factors in prognosis.