Differential reduction in the volume of leiomyoma and uterus during buserelin treatment.

Twenty-four women (mean age 42.0 +/- 2.4 years) with leiomyoma underwent treatment with a gonadotropin releasing hormone (GnRH) agonist (buserelin) for 6 months at a dose of 1200 micrograms daily intranasally for the first 2 months, followed by 900 micrograms daily for 4 months.

[Mixed mesodermal tumors of the uterus. Clinico-pathologic characteristics of 23 patients].

The clinical and pathological features, histogenesis and treatment of 23 cases of mixed mesodermal tumours of the uterus (15 benign and 8 malignant) in woman aged from 27 to 78 years (mean 51.25) are reviewed. The tumours manifested by non-specific symptoms, most often uterine bleeding, arising suspicion of malignancy in only two cases.

[Duplex ultrasonography in the diagnosis of compression of vascular structures at the level of the upper thoracic outlet].

In order to determinate place of compression and degree of haemodynamic disturbance we examined 34 patient and 30 asymptomatic volunteers. By duplex scan we studied retroscalenal part of subclavian artery. Using real-time (B-mode) imaging we founded significant reduction of lumen diameter of subclavian artery during Adsonś, manoeuvre in 51% of cases.

[Retroperitoneal hematoma].

Diagnosis and management of retroperitoneal haematoma is the problem of controversy in actual moment. It appears most frequently in the range of polytrauma or various traumas of abdomen and retroperitoneal organs. Here we report our experience in management of retroperitoneal haematoma.

Recombinations between IRP and cystic fibrosis.

A candidate gene for cystic fibrosis was recently isolated by selective cloning of HpaII-tiny-fragment islands; it maps considerably closer to CF than does MET or D7S8 (pJ3.11), and DNA polymorphisms from this region are in marked disequilibrium with CF. cDNA cloning has shown that this protein has a growth factor-like structure and shows homology to the murine and human proto-oncogene int-1; it is designated IRP (int-1-related protein).