Publications by authors named "Srestha Ghosh"

Exosomes are a subpopulation of extracellular vesicles (EVs) that naturally originate from endosomes. They play a significant role in cellular communication. Tumor-secreted exosomes play a crucial role in cancer development and significantly contribute to tumorigenesis, angiogenesis, and metastasis by intracellular communication.

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Article Synopsis
  • Ruellia tuberosa L. is a traditional medicinal plant known for its various health benefits, particularly its anti-cancer properties, although the detailed mechanisms behind its effects need further exploration.
  • The study aimed to validate the anti-cancer effects of the flower methanolic extract (RTME) specifically against multi-drug resistant triple-negative breast cancer and to investigate the signaling pathways involved.
  • Through various assays, the study found that RTME contains multiple phytochemicals that induce cancer cell damage and apoptosis, showing significant cytotoxic effects and inhibiting cancer cell migration.
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Prostate cancer (PCa) is the second most common and fifth most aggressive neoplasm among men worldwide. In the last decade, extracellular vesicle (EV) research has decoded multiple unsolved cancer-related mysteries. EVs can be classified as microvesicles, apoptotic bodies, and exosomes, among others.

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Cancer is a complex deadly disease that has caused a global health crisis in recent epochs. Colorectal cancer (CRC) is the third most common malignant gastrointestinal disease. It has led to high mortality due to early diagnostic failure.

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