Publications by authors named "Sreenadh Mallavalli"
Background: Topical retinoids are the mainstay of acne therapy and, until 2016, were only available by prescription. The margin of safety (MOS) of adapalene for potential teratogenic effects, and its use in pregnancy were investigated as part of the OTC switch.
Objective: To determine MOS using a maximal usage trial (MUsT) and animal embryo-fetal development studies.