Ultrasound Diagnosis of Pneumothorax in Blunt Chest Trauma: A Correlation Study with Computed Tomography Thorax in Emergency Department Patients at Tertiary Care Centre in Salem, Tamil Nadu.

Introduction: In this study, we compared lung ultrasonography (USG) and computed tomography (CT) findings of the thorax in diagnosing pneumothorax in patients with blunt chest trauma. This study aimed to improve diagnostic accuracy and prevent tension pneumothorax, despite limited evaluations across all lung pathologies.

Methods: We examined patients admitted to Kirupananda Variyar Medical College and Hospital with blunt chest trauma from January 2021 to June 2022.

Buffalopox: An emerging zoonotic challenge.

As a variant of Vaccinia virus, Buffalopox virus is known to cause Buffalopox disease. In recent times, sporadic outbreaks of the infection in humans have been reported, especially in the endemic countries of Southeast Asia. Though mortality has not been high, associated morbidity is significant.

Guillain-barré syndrome (GBS) with antecedent chikungunya infection: a case report and literature review.

Guillain-Barré Syndrome (GBS) is an autoimmune neuropathy. Antecedent infections have been seen to be significant triggering factors for developing GBS. Among them, arboviral infections are rapidly gaining importance as significant triggers, especially in the areas where they are endemic.

Recent cluster of neonatal enteroviral myocarditis cases in the United Kingdom of Great Britain and Northern Ireland - current scenario and counteracting prospects.

Objectives: Neonatal myocarditis is a rare but life-threatening complication of enterovirus infection that presents like bacterial sepsis.

Outbreak: A sudden upsurge in cases of neonatal enteroviral myocarditis, reported from South West England and South Wales between June 2022 and April 2023 has alerted health agencies to bring in counteracting measures.

Impact: In view of this outbreak situation, the World Health Organisation advisory has urged clinicians seeing neonates and infants with shock may consider myocarditis as a differential diagnosis and test for enteroviruses.

Ruthenium-Catalyzed Chemo-Selective Carbene Insertion into C-H Bond of Styrene over Cyclopropanation: C-C Bond Formation.

The C-C bond formation reactions are important in organic synthesis. Heck reaction is known to arylate the terminal carbon of olefins; however, direct alkylation of the terminal carbon of olefin is limited. Herein, we report a novel ruthenium-catalyzed selective cross-coupling reaction of styrene and α-diazoesters to form a new C-C bond over cyclopropanation via the C-H insertion process for the first time.

Protective effects of Cassia tora leaves in experimental cataract by modulating intracellular communication, membrane co-transporters, energy metabolism and the ubiquitin-proteasome pathway.

Context: Cataract is the clouding of eye lens which causes impairment in vision and accounts for the leading factor of global blindness. Functional food-based prevention of cataract finds application in vision research because of its availability and easy access to all classes of the society. Cassia tora Linn.

Polyphenols of Cassia tora leaves prevents lenticular apoptosis and modulates cataract pathology in Sprague-Dawley rat pups.

Cataract is a leading cause of visual impairment worldwide with multifactorial etiology and is a significant global health problem with increasing prevalence with age. Currently, no pharmacological measures are discovered to prevent and treat cataract and a significant number of epidemiological studies have suggested the potential role of antioxidants in the prevention of cataract by scavenging free radicals and preventing lens protein derangement and lenticular cell damage. The main goal of the present study is to evaluate Cassia tora leaves; an edible leafy vegetable employed in Ayurvedic and Chinese system of medicine for eye rejuvenation in preventing selenite-induced cataract in rat pups and to identify the active components that produce the effect.

Anthraquinones and flavonoids of Cassia tora leaves ameliorate sodium selenite induced cataractogenesis in neonatal rats.

The present study was undertaken to evaluate the efficacy of Cassia tora leaves, an edible plant traditionally used for eye ailments, in preventing experimental cataractogenesis. Cataract is the leading cause of irreversible visual impairment worldwide characterized by the cloudiness or opacification of the lens due to the disturbance of even distribution of lens proteins and lipids. A significant number of epidemiological studies have suggested the potential role of herbal medicine in the prevention of cataract by maintaining lens architecture.

Cassia tora leaves modulates selenite cataract by enhancing antioxidant status and preventing cytoskeletal protein loss in lenses of Sprague Dawley rat pups.

Ethnopharmacological Relevance: Cataract is the clouding or opacity that develops in the eye's lens and is considered to be an unavoidable consequence of aging due to irreversible lens damage. Free radicals and oxidant species are reported to be the major factor responsible for the onset and pathology of cataract. No pharmacological measures are formulated to treat cataract blindness and surgical removal of the opaque lens is the only remedy till date.

Luteolin Supplementation Prevents Selenite-Induced Cataractogenesis in Sprague Dawley Rat Pups.

Luteolin, a flavonoid present in leaves and stems of many plants finds mention in literature for beneficial effects on eyes. Presently, no reports are available on the in vivo anticataractogenic effect of luteolin. The current study was designed to evaluate the efficacy of luteolin on selenite-induced cataract models in vivo.