Distinguishing the Bimodal Interaction of a Squaraine Dye with a Protein by a Functional Group Photodeprotection Strategy.

In this study, we present a protecting group photocleavage method to investigate both covalent and noncovalent interactions between a squaraine dye (PSq) and Bovine Serum Albumin (BSA). This approach allows for the photoinduced activation and deactivation of PSq fluorescence, providing valuable insights into the dual-mode interaction of the dye with the protein.

Heavy metals and trace minerals in commonly available shark species from North East Arabian Sea: A human health risk perspective.

Shark is a seafood commodity that is a good source of minerals and accumulates heavy metals and trace elements through biomagnification, which can pose health risk if taken above the permissible limit. A study was conducted on commonly landed eleven shark species (Scoliodon laticaudus, Rhizopriodon oligolinx, Sphyrna lewini (CR), Carcharhinus macloti, Carcharinus limbatus, Carcharhinus amblyrhynchoides, Carcharhinus sorrah, Carcharinus falciformes(VU), Glaucostegus granulatus, Chiloscyllium arabicum, Loxodon macrorhinus) and analyzed for their heavy metal content, Hazard Index, Total Hazard Quotient, Metal Pollution Index, and also calculated the health risk associated with the consumption. Most of the heavy metals and trace minerals were found to be within the acceptable limit.

Segmentation of Brain MRI Images using Multi-Kernel FCM EHO Method.

Background: In image processing, image segmentation is a more challenging task due to different shapes, locations, image intensities, etc. Brain tumors are one of the most common diseases in the world. So, the detection and segmentation of brain tumors are important in the medical field.

A Comparative Analysis of Three Antioxidants in Addition to Scaling and Root Planing in Stage Three Grade B Periodontitis.

Introduction: The main feature of periodontitis is the development of periodontal pockets as a secondary consequence, which is mainly caused by an excessive immune response to the dental biofilm. The prime factor in the pathogenesis of periodontitis is an increase in oxidative stress. Numerous clinical studies have demonstrated that antioxidant supplementation can reduce endogenous antioxidant depletion and the oxidative damage that goes along with it.

Prevalence of Antimicrobial Resistance Among the Hydrogen Sulfide Producing Bacteria Isolated on XLD Agar from the Poultry Fecal Samples.

Poultry products remain as one of the most popular and extensively consumed foods in the world and the introduction of hydrogen sulfide (HS) producing antibiotic resistant bacterial species into it is an emerging challenge. The current study has been designed to analyze the distribution of antibiotic resistance among the HS producing bacteria isolated from the fecal samples of chickens from different poultry farms. Here, twenty bacterial isolates were selected based on their ability to produce HS on XLD agar, and the16S rDNA sequencing was carried out for their molecular identification.

Antineoplastic effects of cassava-cyanide extract on human glioblastoma (LN229) cells.

Several natural compounds reduce tumour cell growth and metastasis by inducing programmed cell death. Cassava (Manihot esculenta Crantz) contains cyanogenic glycosides such as, linamarin and lotaustralin, can be enzymatically cleaved by linamarase to release hydrogen cyanide (HCN), which can have therapeutic benefits against hypertension, asthma, and cancer. We have developed a technology for isolating bio-active principles from cassava leaves.

Analysis of Covid-19 CT chest image classification using Dl4jMlp classifier and Multilayer Perceptron in WEKA Environment.

Introduction: In recent years, various deep learning algorithms have exhibited remarkable performance in various data-rich applications, like health care, medical imaging, as well as in computer vision. Covid-19, which is a rapidly spreading virus, has affected people of all ages both socially and economically. Early detection of this virus is therefore important in order to prevent its further spread.

Genomic insight into the environmental adaptations and toxigenic features of endophytic CaB1 isolated from L.

Unlabelled: In the study, a previously isolated plant beneficial endophytic CaB1 was selected for the detailed analysis by whole-genome sequencing. The WGS has generated a total of 1.9 GB high-quality data which was assembled into a 5,257,162 bp genome with G + C content of 35.

Can Empirical Segmental Angioembolization of Splenic Artery Salvage Pancreatic Intraluminal Bleed?

 Postpancreatectomy hemorrhage (PPH) and Hemosuccus Pancreaticus (HP) may present with slow but significant intraluminal bleed which may not be evident on imaging. We evaluated the efficacy of empirical segmental-angioembolization of splenic artery in intraluminal PPH and HP.  This is a cross-sectional study done by analyzing all consecutive patients with PPH and HP who underwent empirical coil embolization of splenic artery.

Comparative clinical evaluation of a self-adhering flowable composite with conventional flowable composite in Class I cavity: An study.

Context: The purpose of this study was to evaluate the efficiency of self-adhering flowable composite with that of a time-tested conventional flowable composite. Since the self-adhering composite reduces chair time and is convenient to use, its clinical behavior was monitored for a year.

Aim: This study aimed to evaluate the clinical behavior of self-adhering flowable composite - Fusio Liquid Dentin - in small-sized Class I cavities and also to compare it with conventional flowable composite - Tetric N-Flow - bonded to the tooth structure with fifth-generation two-step-etch-and-rinse adhesive.

Rapid detection of mobile resistance genes tetA and tetB from metaplasmid isolated from healthy broiler feces.

Containing antimicrobial resistance is the thought of the moment as it affects the human life from every aspect. Because, the inappropriate use of antibiotics in livestock animals for the growth promotion and prophylactic purpose has already generated significant challenges. The livestock farms which harbor and disseminate drug resistant microorganisms have already been identified as potential source of resistance genes acquired by the sensitive strains.

Design and development of an IoT based intelligent multi parameter screening system.

The SARS-CoV-2 or shortly COVID-19, is a viral disease which causes serious lung fever and hugely impacts different body parts from mild to critical depending on tolerant immune system. As the virus multiplies through human-to-human contact, it has affected our lives in a devastating way, including the vigorous pressure on the public health system, the world economy, education sector, workplaces, and shopping malls. Viral spreading of this virus can only be prevented by early detection of positive cases and to treat infected patients as quickly as possible.

Modulation of Single Atomic Co and Fe Sites on Hollow Carbon Nanospheres as Oxygen Electrodes for Rechargeable Zn-Air Batteries.

Efficient bifunctional electrocatalysts for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are required for metal air batteries, to replace costly metals, such as Pt and Ir/Ru based compounds, which are typically used as benchmarks for ORR and OER, respectively. Isolated single atomic sites coordinated with nitrogen on carbon supports (M-N-C) have promising performance for replacement of precious metal catalysts. However, most of monometallic M-N-C catalysts demonstrate unsatisfactory bifunctional performance.

Altered Cerebrospinal Fluid Exosomal microRNA Levels in Young-Onset Alzheimer's Disease and Frontotemporal Dementia.

Background: micro-RNAs (miRNAs) are stable, small, non-coding RNAs enriched in exosomes. Their variation in levels according to different disease etiologies have made them a promising diagnostic biomarker for neurodegenerative diseases such as Alzheimer's disease (AD). Altered expression of miR-320a, miR-328-3p, and miR-204-5p have been reported in AD and frontotemporal dementia (FTD).

Effect of cyanide ions (CN-) extracted from cassava (Manihotesculenta Crantz) on Alveolar Epithelial Cells (A549 cells).

Cassava (Manihotesculenta Crantz) is one of the most important root crops in tropical countries. It is a major source of cyanogenic glycosides viz. linamarin and lotaustralin, and these on breakdown liberate HCN and ketone.

Corrigendum: A Molecular CO Reduction Catalyst Based on Giant Polyoxometalate {Mo}.

[This corrects the article DOI: 10.3389/fchem.2018.

An Anthracene-Based Metal-Organic Framework for Selective Photo-Reduction of Carbon Dioxide to Formic Acid Coupled with Water Oxidation.

A Zr-based metal-organic framework has been synthesized and employed as a catalyst for photochemical carbon dioxide reduction coupled with water oxidation. The catalyst shows significant carbon dioxide reduction property with concomitant water oxidation. The catalyst has broad visible light as well as UV light absorption property, which is further confirmed from electronic absorption spectroscopy.

Genome sequencing and annotation of multi-virulent Aeromonas veronii XhG1.2 isolated from diseased Xiphophorus hellerii.

The present study was intended to elucidate the genomic basis of antibiotic resistance and hyper-virulence of the fish pathogen Aeromonas veronii XhG1.2 characterized in our previous work. The identity of XhG1.

Healthy broilers disseminate antibiotic resistance in response to tetracycline input in feed concentrates.

Wide varieties of antibiotics are used in poultry farms to improve the growth and also to control the infection in broiler chicken. To identify the seriousness of the same in the poultry sector, current study has been designed to analyze the presence of tetracycline in poultry feed and also the tetracycline resistance among the bacteria released through the excreta of poultry. In the study, 27 bacteria belonging to the Escherichiacoli and Klebsiellapneumoniae.

Clinical data classification using an enhanced SMOTE and chaotic evolutionary feature selection.

Class imbalance and the presence of irrelevant or redundant features in training data can pose serious challenges to the development of a classification framework. This paper proposes a framework for developing a Clinical Decision Support System (CDSS) that addresses class imbalance and the feature selection problem. Under this framework, the dataset is balanced at the data level and a wrapper approach is used to perform feature selection.

Size exclusion chromatography: An effective tool for the estimation of Sirolimus levels.

Sirolimus, a lipophilic macrolide, is a well-known immunosuppressant drug used for coating coronary stents and for preventing rejection of kidney transplants in humans. Since Sirolimus is a relatively large molecule with an average mass 914.172 g/mol, size exclusion chromatography (SEC) was employed for exploring its potential for the estimation of Sirolimus content from blood samples.

Electrocatalytic Reduction of CO to Acetic Acid by a Molecular Manganese Corrole Complex.

The controlled electrochemical reduction of carbon dioxide to value added chemicals is an important strategy in terms of renewable energy technologies. Therefore, the development of efficient and stable catalysts in an aqueous environment is of great importance. In this context, we focused on synthesizing and studying a molecular Mn -corrole complex, which is modified on the three meso-positions with polyethylene glycol moieties for direct and selective production of acetic acid from CO .

Surface-Modified Hollow Ternary NiCoP Catalysts for Efficient Electrochemical Water Splitting and Energy Storage.

Generally, a cost-effective electrocatalytic process that offers an efficient electrochemical energy conversion and storage necessitates a rational design and selection of structure as well as composition of active catalytic centers. Herein, we achieved an unprecedented surface morphology and shape tuning to obtain hollow NiCoP with a continuum of active sharp edges (spiked) on a hollow spherical surface by means of facile hydrothermal treatments. The highly exposed, branched spike-covered hollow structure of NiCoP shows remarkable performance enhancement for hydrogen evolution reaction and oxygen evolution reaction in a wide range of Ph solutions.

Molecular cobalt corrole complex for the heterogeneous electrocatalytic reduction of carbon dioxide.

Electrochemical conversion of CO to alcohols is one of the most challenging methods of conversion and storage of electrical energy in the form of high-energy fuels. The challenge lies in the catalyst design to enable its real-life implementation. Herein, we demonstrate the synthesis and characterization of a cobalt(III) triphenylphosphine corrole complex, which contains three polyethylene glycol residues attached at the meso-phenyl groups.