Publications by authors named "Sree Gowrinadh Javvadi"

Diet-microbe interactions play an important role in modulating the early-life microbiota, with Bifidobacterium strains and species dominating the gut of breast-fed infants. Here, we sought to explore how infant diet drives distinct bifidobacterial community composition and dynamics within individual infant ecosystems. Genomic characterisation of 19 strains isolated from breast-fed infants revealed a diverse genomic architecture enriched in carbohydrate metabolism genes, which was distinct to each strain, but collectively formed a pangenome across infants.

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Article Synopsis
  • Azelaic acid is a dicarboxylic acid found in cereals that recently shows potential in plant-bacteria interactions and can be used by certain bacteria as a carbon and energy source.
  • In this research, a specific bacterium, DSM 9128, is used to investigate how it degrades azelaic acid and how it reacts to it genetically.
  • The study reveals that mutations in specific genes hinder the growth of bacteria in azelaic acid and identifies a regulator named AzeR that responds to azelaic acid, which is limited to certain bacteria that can utilize it.
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Background: Pseudomonas syringae pv. actinidiae (PSA) is an emerging kiwifruit bacterial pathogen which since 2008 has caused considerable losses. No quorum sensing (QS) signaling molecule has yet been reported from PSA and the aim of this study was to identify possible intercellular signals produced by PSA.

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Bacterial canker disease caused by Pseudomonas syringae pv. actinidiae, an emerging pathogen of kiwifruit plants, has recently brought about major economic losses worldwide. Genetic studies on virulence functions of P.

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Synopsis of recent research by authors named "Sree Gowrinadh Javvadi"

  • - Sree Gowrinadh Javvadi’s research primarily focuses on the interactions between diet and microbiota, particularly examining how breast milk oligosaccharides influence Bifidobacterium species in infants and their role in shaping gut microbiota composition.
  • - In addition to studies on human health, Javvadi explores the use of azelaic acid in plant-bacteria signaling and the metabolic pathways bacteria employ to utilize this compound, demonstrating its significance in microbial ecology.
  • - Javvadi also investigates plant pathogens, specifically Pseudomonas syringae, revealing insights into its lipolytic activity and the genetic factors contributing to its virulence in kiwifruit, highlighting the economic impact of this bacterial disease.