Publications by authors named "Srdjan J Rakic"
Article Synopsis
- Researchers created a complex of biochanin A (BCA) with (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD) using ethanol to boost BCA's water solubility.
- They analyzed the complex using various methods like FTIR, H-NMR, and SEM and found that the solubility of BCA doubled in a 42% ethanol solution after forming the complex.
- The study revealed that while the antimicrobial activity of BCA was preserved post-complexation, the complex was less effective against certain bacteria but showed increased activity against Candida albicans.
Purpose: The aim of the paper was to develop the simple procedures for preparation of inclusion complexes of ellagic acid (EA) with cyclodextrins (CDs) and to investigate their antioxidant and antimicrobial activity.
Methods: The structural characterization was carried out using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and nuclear magnetic resonance (NMR) methods. The phase solubility technique was used to investigate the interactions between 'host' and 'guest' molecules and to estimate the molar ratio between them.