Subcutaneous administration of foslevodopa/foscarbidopa (PRODUODOPA) in arm and thigh due to giant epigastric hernia: a case report.

Background: PRODUODOPA is a combination of foscarbidopa and foslevodopa indicated for the treatment of motor fluctuations in patients with advanced Parkinson's disease when available combinations of peroral drugs have not given satisfactory results. The solution is administered via subcutaneous infusion, most frequently in the abdomen, using an infusion pump. The study results showed a significant effect on the reductions in off time and higher control of motor symptoms without troublesome dyskinesia.

Relationship of restless legs syndrome with number of pregnancies, duration of pregnancy and positive family history.

Objectives: The aim of this cross-sectional study was to examine the correlation between gestational age and number of previous pregnancies in group of pregnant women with restless legs syndrome and the connection of restless legs syndrome with family history positive versus family history negative group of pregnant and non-pregnant women.

Methods: Four hundred and sixty-two women were involved in this study: 231 pregnant women and the same number of non-pregnant women of compatible age as a control group. We defined restless legs syndrome as presence of International Restless Legs Syndrome Study Group criteria.

On Differences between Gilles de la Tourette Syndrome and Psychogenic/Functional Tics: A Narrative Review.

A tic is a sudden, rapid, recurrent, nonrhythmic motor movement or vocalization. Motor and phonic tics in a course of over 1 year that first occured before 18 years are the main features of Gilles de la Tourette syndrome (GTS). Psychogenic/functional (P/F) tics were considered as a diagnosis made per exlusionem in lack of agreement of diagnostic criteria.

ATP7B Gene Mutations in Croatian Patients with Wilson Disease.

Aims: Wilson disease (WD) is an autosomal recessive disorder of copper metabolism, characterized by its accumulation in tissues which results in hepatic, neurological, and/or psychiatric symptoms. The aim of this study was to investigate the genetics of WD in Croatian patients.

Methods: Correlation of the clinical presentation subtype and the age at onset of the diagnosis of WD with the ATP7B genotype was investigated in a group of Croatian WD patients.

Symptomatic capillary telangiectasia of the pons and intracerebral developmental venous anomaly - A rare association.

Various combinations of vascular malformations of the brain in one lesion have been reported, while others seem to be very rare. In this report, the authors discuss the case of a coexistence of an capillary telangiectasia of the pons and intracerebral venous anomaly. To our knowledge, this is the first report of coexistence of a capillary telangiectasia of the pons and intracerebral venous anomaly apparted from each other.

Coexistence of intradural spinal arteriovenous malformation and associated developmental anomalies - report of two cases.

Spinal arteriovenous malformations (AVM) have been devided into dural (Type I), intramedullary glomus (Type II), juvenile (Type III), and perimedullary direct arteriovenous fistulae (Type IV). AVMs are usually associated with subacute myelopathy in what has been known as Foix-Alajouanine syndrome. We presented two patients with two intradural spinal arteriovenous malformations associated in what we call Foix-Alajouanine syndrome.

[Tremor--clinical features].

Tremor is the commonest hyperkinesia in humans, often very impressive in its manifestation not only for patients and their families but also for physicians themselves. As a variety of etiological factors, diseases, conditions and substances that can cause it, this clinical entity is a recurrent differential diagnostic problem, that sometimes, unfortunately, results in diagnostic and therapeutic failures. Relative therapeutic resistance of some types of tremor, along with ineffective treatment and frequent iatrogenic potential, makes an additional problem in everyday clinical practice.

Restless legs syndrome in hemodialysis patients: association with calcium antagonists. A preliminary report.

Uremia-related restless legs syndrome (RLS) is a known form of secondary RLS. This cross-sectional survey included patients (n = 82) on stable hemodialysis (HD; >3 months, Kt/V >1.2) who were iron-replete, free of neurodegenerative or psychiatric disorders, severe polyneuropathy and radiculopathy, not exposed to antipsychotics/antidepressants, and not severely anemic.

[Cyclosporine-induced depressive psychosis in a liver transplant patient: a case report].

Psychotic conditions of iatrogenic nature form a non-negligible portion of psychiatric practice. In this paper we present a case of a 62-year-old patient with the primary diagnosis of autoimmune hepatitis-induced cirrhosis who following the orthotopic liver transplantation developed an episode of depressive psychosis. The appearance of symptoms and signs directly correlated with the administration of the maximal dose of cyclosporine.

Impact of war on central nervous system tumors incidence--a 15-year retrospective study in Istria County, Croatia.

The aim of study was to analyze epidemiological features of central nervous system (CNS) tumors diagnosed in Istria County, Croatia, with a particular emphasis on incidence dynamics during the wartime (1991-1995). The data were extracted from the medical records of patients with CNS tumors admitted to the Department of Neurology of Pula General Hospital in the period from the 1st January 1986 to the 31st December 2000, N = 364. For calculation of rates, we used data from the 2001 Croatian consensus http://www.

Botulinum toxin in tension-type headache.

Despite the controversy regarding specific mechanism of botulinum toxin action in pain relief, clinical results suggest that botulinum toxin type A may be promising treatment options for patients with primary chronic headache. To investigate this, we included sixteen patients with chronic tension-type headache in a prospective double blind, placebo-controlled crossover study and thirty patients in an open-label long-term study. All of the patients showed reduced severity of headache, reduced pericranial muscle tenderness and increased headache-free days during botulinum toxin A treatment.