Publications by authors named "Srawani Sarkar"

Background: Gastric cancer (GC) is the fifth leading cause of cancer-related death worldwide. The oral microbiota was investigated for distinguishable characteristics between GC, premalignant gastric conditions (Pre-GC), and control participants.

Methods: Mouthwash samples from GC, Pre-GC, and control participants at a tertiary care center were prospectively collected.

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Purpose: Gastric cancer (GC) incidence rates show notable differences by racial/ethnic groups in the US. We sought to determine whether stratification by race/ethnicity would reveal unique risk factors for development of non-cardia gastric cancer (NCGC) for US population.

Methods: Analysis included 1,112 incident cases of NCGC and 190,883 controls from the Multiethnic Cohort Study, a prospective US cohort study that recruited individuals living in Hawaii and California, aged 45-75 years from 5 races/ethnicities.

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Article Synopsis
  • * A meta-analysis of 26 clinical trials found that patients receiving BVZ had a fourfold increase in the odds of developing hypertension and more than double the odds of arterial thromboembolism compared to those on chemotherapy alone.
  • * The results emphasize the need to weigh the risks, especially for patients with existing vascular conditions, when considering adding BVZ to their treatment regimen.
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Objective: Gastric cancer (GC) disproportionately affects ethnic minorities in the US including Asians and Pacific Islanders. Research with minority groups who are at high risk are needed to provide more effective treatment. Successful recruitment of minorities to research must overcome obstacles of language, access, fear and mistrust.

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Article Synopsis
  • Cancer is often diagnosed through routine screening, but a significant number of gastrointestinal (GI) cancers (23%-52%) are detected in emergency departments (ED), resulting in poorer health outcomes for patients.
  • The study involved interviewing patients who were diagnosed with GI cancer after visiting the ED, focusing on their experiences and factors influencing their diagnosis.
  • Key findings revealed that patients faced issues like denial of symptoms, lack of trust in healthcare, misdiagnosis, and delays in receiving care, emphasizing the need for better public awareness and healthcare system improvements for timely cancer diagnosis.
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Background: Gastric cancer lacks specific symptoms, resulting in diagnosis at later stages and high mortality. Serum pepsinogen is a biomarker for atrophic gastritis, a gastric cancer precursor, and may be useful to detect persons at increased risk of gastric cancer.

Methods: The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial was conducted in the United States between 1993 and 2001.

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Introduction: Socioeconomic status (SES) is a known risk factor for gastric cancer (GC). This study seeks to examine education, income, and occupation variables separately to identify the single variable that can be best used to assess SES risk for GC.

Methods: Data from a case-control survey study were used.

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Background: Percutaneous cholecystostomy (PC) tube is a preferred option in acute cholecystitis for patients who are high risk for cholecystectomy (CCY). There are no evidence-based guidelines for patient care after PC. We identified the predictors of disease recurrence and successful interval CCY.

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